Actively Recruiting
Comparing Full Sternotomy and J-shaped Mini-sternotomy for Repairing Chronic Ascending Aortic Aneurysm
Led by Tomsk Cardiology Research Institute · Updated on 2026-02-05
200
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
This research aims to compare outcomes after hemiarch repair in patients with chronic ascending aortic disease, specifically ascending aortic aneurysm larger than 5 cm. The study evaluates two surgical approaches the traditional full sternotomy and the less invasive J-shaped mini-sternotomy. Researchers want to assess differences in early and late complications, including mortality, morbidity, and recovery factors. Patients will be divided into two groups of 100 each, undergoing hemiarch repair either through full sternotomy or J-shaped mini-sternotomy. Both procedures involve mild-to-moderate hypothermia and cerebral perfusion during surgery, with detailed surgical steps consistent across groups. Imaging assessments using computed tomography will be done before and after surgery to measure aortic dimensions and monitor repair success. Participants will be followed for up to 60 months, with postoperative CT scans at discharge, 12 months, and 60 months. Researchers will collect data on mortality, stroke, heart complications, kidney injury, and other outcomes through medical records and follow-up contact. The study will track early and late effects of each surgical method to help understand the benefits and risks of minimally invasive versus traditional surgery for ascending aortic aneurysm.
CONDITIONS
Brief Title
Full Sternotomy vs Mini-sternotomy for Ascending Aortic Pathology
Research Team
D
Dmitri S. Panfilov, MD, PhD
A
Andrey V. Sofronov
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