Study of Stomach and Esophagus Function After One Anastomosis Gastric Bypass Surgery OAGB

What this Trial Is About

Researchers are evaluating the functional changes in the stomach and esophagus of patients undergoing One Anastomosis Gastric Bypass OAGB. This study aims to assess various risk factors such as age, gender, tobacco and alcohol use, medications, and health conditions for the development of marginal ulcers after surgery, as well as other outcomes related to weight loss and gastrointestinal health. The research is sponsored by Spital Limmattal Schlieren and focuses on patients with obesity and related conditions like GERD and gastric ulcers. Participants will undergo the OAGB procedure performed laparoscopically. The surgery involves dividing the stomach and connecting it to the small bowel at a point about 200 cm from the ligament of Treitz. This creates a new pathway for food to bypass part of the stomach and small intestine. The study tracks patients after surgery to monitor changes and complications over time. Throughout the study, participants will be followed for up to 5 years post-surgery. Researchers will monitor marginal ulcer rates, weight loss percentages, changes in esophageal function, reflux events, and quality of life related to gastrointestinal and obesity issues. Assessments include endoscopy, manometry, impedance pH-metry, and questionnaires to evaluate reflux symptoms and life quality. Safety and long-term effects will be carefully observed to understand the impact of OAGB on stomach and esophagus function.

Functional Changes in the Stomach and Esophagus After One Anastomosis Gastric Bypass- OAGB