Actively Recruiting
Functional Incremental Stepping in Place Test (F-IST) Validation
Led by Kirby Mayer · Updated on 2026-03-17
60
Participants Needed
2
Research Sites
104 weeks
Total Duration
On this page
Sponsors
K
Kirby Mayer
Lead Sponsor
D
Duke University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this multi-site prospective study is to assess validity of a new step test called Functional-Incremental Stepping-in-place- Test (F-IST) compared to gold-standard cardiopulmonary exercise testing (CPET) and to physical function and health perception, respectively. The investigators will also assess test-retest reliability of the F-IST. The investigators hypothesize that the F-IST will have high validity and test-retest reliability to be used in field testing environments such as the ICU.
CONDITIONS
Official Title
Functional Incremental Stepping in Place Test (F-IST) Validation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Currently able to walk with or without a walking aid, such as a cane or walker or rollator
You will not qualify if you...
- Pregnancy
- Recent significant change in resting ECG
- Unstable angina
- Uncontrolled cardiac dysrhythmias causing symptoms or hemodynamic compromise
- Symptomatic severe aortic stenosis
- Uncontrolled symptomatic heart failure
- Acute pulmonary embolus or pulmonary infarction
- Acute myocarditis or pericarditis
- Suspected or known dissecting aneurysm
- Acute systemic infection with fever, body aches, or swollen lymph glands
- Left Main Coronary Stenosis
- Moderate stenotic valvular heart disease
- Electrolyte abnormalities
- Severe arterial hypertension (>200 systolic, >110 diastolic) at rest
- Tachydysrhythmia or bradydysrhythmia
- Hypertrophic cardiomyopathy and other outflow tract obstruction
- Neuromuscular, musculoskeletal, or rheumatic disorders exacerbated by exercise
- High degree AV block
- Ventricular aneurysm
- Uncontrolled metabolic disease (diabetes, thyrotoxicosis, or myxedema)
- Chronic infectious disease (hepatitis, AIDS, mono)
- Mental or physical impairment leading to inability to exercise adequately
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Florida Atlantic University
Boca Raton, Florida, United States, 33431
Actively Recruiting
2
Duke University
Durham, North Carolina, United States, 27708
Actively Recruiting
Research Team
R
Research Associate Senior
CONTACT
P
Primary Investigator
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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