Comparing Functional and Monofocal Intraocular Lens Implantation in Cataract Patients with Macular Epiretinal Membrane

What this Trial Is About

This research aims to evaluate macular involvement and epiretinal membrane ERM grading using OCT in eyes with ERM and to compare clinical outcomes after implanting Enhance intraocular lenses IOL versus standard monofocal IOLs in patients with ERM. The study focuses on whether functional IOLs provide benefits for patients with ERM undergoing cataract surgery. It is a prospective, multicenter, interventional study involving cataract patients diagnosed with grade-1 macular ERM. Participants diagnosed with ERM will choose between receiving either a functional IOL or a monofocal IOL during cataract surgery. The follow-up period for the study is two years. The primary outcome is visual acuity measured at various distances 5 meters, 66 cm, and 40 cm using standard visual acuity charts. Secondary outcomes include OCT and Amsler grid tests, measurements of higher-order aberrations, modulation transfer function, defocus curves, contrast sensitivity under different lighting conditions, reading ability tests, and questionnaires assessing functional vision and photic phenomena. Participants will have scheduled visits at baseline, 1 day, 1 week, 1 month, 3 months, 6 months, 1 year, and 2 years after surgery. At each visit, researchers will perform visual acuity exams, OCT imaging, contrast sensitivity testing, and reading tests. Questionnaires will assess vision-related quality of life and photic symptoms. These assessments help compare the visual outcomes and satisfaction between the functional IOL and monofocal IOL groups throughout the two-year follow-up.

Functional IOL Implantation in Patients With Epiretinal Membrane