Actively Recruiting
Functional Magnetic Stimulation (FMS) for Bone Marrow Edema in Athletes
Led by International Hellenic University · Updated on 2025-11-18
40
Participants Needed
1
Research Sites
43 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This randomized controlled trial investigates the effectiveness of Functional Magnetic Stimulation (FMS) as an adjunct to physiotherapy in athletes with MRI-confirmed bone marrow edema of the lower limb. Forty athletes with Fredericson grade 2-3 edema will be randomly assigned to receive either physiotherapy plus FMS or physiotherapy alone for four weeks. Clinical, functional, and imaging assessments will be conducted up to 16 weeks. Primary outcomes include pain intensity, lower-limb function, return-to-sport readiness, and MRI indicators of bone marrow edema. The study aims to determine whether adjunctive FMS enhances recovery and accelerates the resolution of bone marrow edema compared with standard physiotherapy.
CONDITIONS
Official Title
Functional Magnetic Stimulation (FMS) for Bone Marrow Edema in Athletes
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Athletes aged 18-45 years participating in regular sports training 63 sessions per week for the past 6 months
- MRI-confirmed bone marrow edema of the lower limb graded as Fredericson 2 or 3
- Pain or symptoms started within the previous 6 weeks
- Pain intensity 64 out of 10 on the Numeric Rating Scale during loading activity
- Ability to comply with the 4-week intervention and 16-week follow-up assessments
- Written informed consent provided prior to participation
You will not qualify if you...
- Fredericson grade 4 or evidence of a fracture line on MRI
- Bone marrow edema caused by infection, tumor, or systemic inflammatory disease
- History of recent fracture, surgery, or intra-articular injection in the affected limb within 12 weeks
- Prior Functional Magnetic Stimulation or Extracorporeal Shockwave Therapy within 8 weeks before enrollment
- Presence of metallic implants, pacemaker, or other contraindications to magnetic stimulation
- Pregnancy or breastfeeding
- Use of systemic corticosteroids or medications affecting bone metabolism
- Any neurological, metabolic, or cardiovascular condition interfering with safe participation
AI-Screening
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Trial Site Locations
Total: 1 location
1
Department of Physiotherapy, Faculty of Health Sciences International Hellenic University
Thessaloniki, Sindos, Greece, 57400
Actively Recruiting
Research Team
D
Dimitrios Lytras, PhD
CONTACT
P
Paris Iakovidis, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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