Actively Recruiting

Age: 6Years - 40Years
All Genders
Healthy Volunteers
NCT06703736

Functional and Morphological Characterization of Multiple Osteochondromas Disorder

Led by Istituto Ortopedico Rizzoli · Updated on 2026-03-24

60

Participants Needed

1

Research Sites

84 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The main purpose of the study is the characterization of functional and morphological alterations due to multiple osteochondromas in a pediatric and adult population through the identification of relevant anthropometric and functional parameters. The morphological and functional data, supplemented with clinical and postural data, will allow the characterization of the disease with an holistic approach that can provide important information to properly assess timing for surgical treatments and to improve the quality of life of these patients. Another goal of the study is the assessment and the validation of novel instruments and tools to measure joint mobility and bone deformity. These instruments should be easy-to-use and designed to be operated locally by the patients themselves and/or in small clinics by operators with little training and no specific high-technical knowledge. The final goal of the study is the assessment of the quality of life and balance perception of patients, using questionnaires.

CONDITIONS

Official Title

Functional and Morphological Characterization of Multiple Osteochondromas Disorder

Who Can Participate

Age: 6Years - 40Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinical and/or molecular diagnosis of Multiple Osteochondromas (for patient group)
  • Male or female subjects
  • Age between 6 and 17 years (minors) or 18 and 40 years (adults) at enrollment
  • Signed informed consent obtained
  • Ability to walk a straight path without aids
  • Presence of multiple osteochondromas on lower limbs (for patient group)
  • Ability to undergo all required study procedures
  • Absence of neuro-musculoskeletal or other limb-limiting conditions in lower limbs (for healthy group)
Not Eligible

You will not qualify if you...

  • Not meeting all inclusion criteria
  • Any condition that would prevent following the study protocol as judged by the investigator
  • Body mass index (BMI) of 30 or higher

AI-Screening

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Trial Site Locations

Total: 1 location

1

IRCCS Istituto Ortopedico Rizzoli

Bologna, Italy, 40136

Actively Recruiting

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Research Team

P

Paolo Caravaggi, PhD, Engineer

CONTACT

M

marina mordenti, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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