Actively Recruiting
Functional MRI for Monitoring Progression and Assessing Trends in ILD
Led by University Hospital Heidelberg · Updated on 2025-12-24
200
Participants Needed
2
Research Sites
84 weeks
Total Duration
On this page
Sponsors
U
University Hospital Heidelberg
Lead Sponsor
G
German Center for Lung Research
Collaborating Sponsor
AI-Summary
What this Trial Is About
The main objective of this study is to investigate the utility of functional MRI to differentiate, characterize, and monitor subgroups of ILD. This can be broken down into three specific objectives: Determine if ILD features observed on high-resolution computed tomography (HRCT), such as ground glass opacities (GGO), are functionally different. Analyse MRI metrics within each subgroup to determine whether these metrics distinguish different ILDs. Assess MRI metrics longitudinally to see if these parameters change with disease progression, stability, or reversibility.
CONDITIONS
Official Title
Functional MRI for Monitoring Progression and Assessing Trends in ILD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical indication for routine HRCT due to newly diagnosed or suspected idiopathic pulmonary fibrosis, hypersensitivity pneumonitis, or idiopathic non-specific interstitial pneumonia, or for follow-up
- Ability to provide informed consent
- Ability to lie still during imaging to participate fully in the study
You will not qualify if you...
- Pregnancy or breastfeeding
- Under 18 years of age or unable to give informed consent
- Medical conditions preventing adherence to the study protocol
- Any MRI contraindications, including allergic reactions to gadolinium-based contrast or kidney dysfunction (eGFR < 30 ml/min/1.73 m2)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Thoraxklink Heidelberg - Universitätsklinikum Heidelberg
Heidelberg, Germany, 69126
Actively Recruiting
2
Universitätsklinikum Schleswig-Holstein, Campus Kiel
Kiel, Germany, 24105
Active, Not Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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