Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT05719415

Functional Pulmonary Capillary Surface Area in BPA for CTEPH

Led by Jewish General Hospital · Updated on 2025-09-23

40

Participants Needed

1

Research Sites

253 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Chronic thromboembolic pulmonary hypertension \[CTEPH\] is caused by pulmonary emboli that have enlarged in pulmonary arteries and have become organized into the vessel wall. Many patients with CTEPH are treated with balloon pulmonary angioplasty \[BPA\] which mechanically opens the narrow pulmonary arteries. It is unclear how much downstream functional pulmonary capillary surface area \[FCSA\] is recovered during BPA. The investigators plan to measure FCSAIn CTEPH patients, before and after a session of BPA.

CONDITIONS

Official Title

Functional Pulmonary Capillary Surface Area in BPA for CTEPH

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Eligible for balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension
Not Eligible

You will not qualify if you...

  • Treatment with angiotensin-converting enzyme inhibitors or angiotensin receptor blockers
  • Presence of patent foramen ovale

AI-Screening

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Trial Site Locations

Total: 1 location

1

David Langleben

Montreal, Quebec, Canada, H3W 2C4

Actively Recruiting

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Research Team

D

David Langleben, MD

CONTACT

L

Lyda Lesenko, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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