Actively Recruiting
Fundus Camera Module for Early Detection of Alzheimer's Disease
Led by I.R.C.C.S. Fondazione Santa Lucia · Updated on 2025-02-24
80
Participants Needed
1
Research Sites
147 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Alzheimer's Disease (AD) affects tens of millions of people just in Europe. It is typically detected in its late stage when irreversible damage has already occurred, and current treatments are mostly conservative or palliative. Here we developed a device performing high-resolution multispectral imaging of the eye fundus to detect AD in its early stage. After clinical testing, the proposed device has a high potential to become a method for routine population screening, as it is non-invasive and affordable. The possibility of AD detection in an early stage is crucial for developing a new pharmaceutical treatment that would dramatically improve the lives of millions and save the expenses connected to lifelong healthcare assistance to people with AD in later stages.
CONDITIONS
Official Title
Fundus Camera Module for Early Detection of Alzheimer's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 55 years or older
- For AD group: Clinically diagnosed with Alzheimer's disease (mild to moderate stage) based on Mini-Mental State Examination (MMSE) score between 10-26 and confirmed by PET imaging or CSF
- For Control group: No diagnosis of Alzheimer's disease or other neurodegenerative disorders
- Signed informed consent by the patient, with mental capability verified if there is any doubt
You will not qualify if you...
- Severe cognitive impairment (MMSE <10) preventing cooperation during the imaging process
- Inability to remain still during the fundus imaging procedure
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Santa Lucia Foundation
Rome, Italy, Italy, 00179
Actively Recruiting
Research Team
F
Francesco Di Lorenzo, Dott
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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