Fusion Imaging in Endovascular Thrombectomy for Acute Ischemic Stroke

What this Trial Is About

Researchers are evaluating the use of fusion imaging during endovascular thrombectomy (EVT) procedures for acute ischemic stroke caused by large vessel occlusion. This study aims to assess whether fusion imaging can improve target vessel access, increase recanalization success rates, and reduce procedure times compared to standard EVT. Fusion imaging involves combining 3D reconstructions from preprocedural CT angiography with live 2D angiography during the procedure. Participants will be randomly assigned to receive either standard EVT with fusion imaging or standard EVT without fusion imaging. Fusion imaging is performed using the ARTIS Icono Biplane system and includes steps such as importing CT angiography images, removing bone structures, and overlaying vascular landmarks onto live fluoroscopy. The fusion process is done quickly during patient preparation and does not add radiation or prolong the procedure. The study is multinational and multicenter, enrolling approximately 300 patients. During the study, researchers will collect data from national or local quality registries or a study database. They will monitor procedure success rates, vessel access, recanalization times, and other outcomes using imaging core lab adjudication. Safety is monitored, but fusion imaging does not add procedural risk or radiation exposure. The study lasts until three months after the last patient is included, and participant data is handled securely and anonymously.

Fusion Imaging in Endovascular Thrombectomy for Acute Ischemic Stroke