Actively Recruiting
Ga-68-CXCR4 PET/CT in Indolent B-cell Lymphoma
Led by Koo Foundation Sun Yat-Sen Cancer Center · Updated on 2024-06-14
15
Participants Needed
1
Research Sites
152 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study explores the efficacy of Ga-68-PentixaFor PET/CT in detecting, assessing treatment response, and monitoring the risk of aggressiveness in indolent B-cell lymphoma. The background introduces CXCR4 and discusses its role in cancer research. Currently, FDG-PET is the primary imaging tool for lymphoma staging, but it lacks diagnostic accuracy for low-grade lymphomas. Ga-68-PentixaFor PET demonstrates promising detection capabilities across various lymphomas, suggesting its potential as a superior imaging modality for low-grade lymphomas.
CONDITIONS
Official Title
Ga-68-CXCR4 PET/CT in Indolent B-cell Lymphoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pathological diagnosis of slow-growing lymphoma such as marginal-zone B-cell lymphoma, Waldenstrom macroglobulinemia lymphocytic lymphoma, CLL/SLL, or mantle cell lymphoma
- Have undergone or plan to undergo an FDG PET scan for initial staging, treatment response evaluation, or follow-up within 3 to 6 months
- Able to lie flat for at least 30 minutes during the PET/CT procedure
- Signed informed consent form
- Eastern Cooperative Oncology Group (ECOG) performance status grade 0 to 2
- Timing of F-18-FDG use follows institutional lymphoma treatment principles
You will not qualify if you...
- Pregnant women
- Severe renal impairment (eGFR less than 30 ml/min)
- Known or suspected allergy to radiopharmaceuticals
- Current or previous cancer diagnosis other than lymphoma
- Unable to undergo PET scan procedure
- Refusal or unwillingness to sign informed consent
- Severe medical conditions such as severe disabilities or mental disorders
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Koo Foundation Sun Yat-Sen Cancer Center
Taipei, Beitou, Taiwan, 1125019
Actively Recruiting
Research Team
Y
Yu Yi Huang, MD
CONTACT
C
Cheng Ling Yang, B.Rad.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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