Actively Recruiting
68Ga-DOTATATE PETMRI in the Diagnosis and Management of Somatostatin Receptor Positive Central Nervous System Tumors
Led by Weill Medical College of Cornell University · Updated on 2025-11-21
200
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
W
Weill Medical College of Cornell University
Lead Sponsor
N
Novartis Pharmaceuticals
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating the use of Gallium-68-DOTATATE PETMRI in patients with somatostatin receptor-positive SSTR-positive central nervous system CNS tumors, mainly focusing on meningioma but also including other tumor types such as esthesioneuroblastoma, hemangioblastoma, medulloblastoma, paraganglioma, pituitary adenoma, and SSTR-positive systemic cancers metastatic to the brain. The study aims to assess the diagnostic usefulness of this imaging technique, especially in distinguishing tumor recurrence from post-treatment changes, with a particular interest in cases where tumor location limits surgical removal or where patients have higher-grade disease or previous radiation treatment. This is a Phase 4 interventional study sponsored by Weill Medical College of Cornell University.
CONDITIONS
Brief Title
68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age or older
- Diagnosis of meningioma confirmed by pathology with suspected recurrence or residual disease on standard MRI
- Patients with other somatostatin receptor 2 positive brain tumors such as esthesioneuroblastoma, hemangioblastoma, medulloblastoma, paraganglioma, pituitary adenoma, or SSTR-positive systemic cancers metastatic to the brain
- Ability to undergo 3 Tesla MRI or 1.5 Tesla MRI with PET/CT imaging as per clinical standards
You will not qualify if you...
- Contraindications to gadolinium-based contrast agents
- History of allergic reaction to Gallium-68-DOTATATE
- Pregnancy
Research Team
J
Jana Ivanidze, MD/Ph.D
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here