Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06451536

Ga-68 FAPI PET Before Immunotherapy

Led by Ankara University · Updated on 2024-06-11

30

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

Sponsors

A

Ankara University

Lead Sponsor

L

Liv Hospital Ankara

Collaborating Sponsor

AI-Summary

What this Trial Is About

It is aimed to evaluate FAP expression and its success in predicting treatment response before immunotherapy used in the treatment of malignant mesothelioma with Ga68 FAPI PET/CT imaging, which allows in vivo evaluation of FAP expression, which is thought to be associated with immunosuppression and resistance to immunotherapy.

CONDITIONS

Official Title

Ga-68 FAPI PET Before Immunotherapy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Histopathologically confirmed diagnosis of pleural mesothelioma
  • Scheduled for immunotherapy with anti-PDL-1 and/or anti-CTLA-4 antibodies as first or second line therapy
  • Provided informed consent to participate in the study
Not Eligible

You will not qualify if you...

  • Eastern Cooperative Oncology Group (ECOG) performance status greater than 2
  • Did not provide informed consent to participate in the study

AI-Screening

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Trial Site Locations

Total: 1 location

1

Ankara University School of Medicine

Ankara, Turkey (Türkiye), 06590

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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