Actively Recruiting
Ga68-FAPI-46 PET/CT for Preoperative Assessment of Peritoneal Carcinomatosis
Led by Jules Bordet Institute · Updated on 2025-03-31
80
Participants Needed
1
Research Sites
130 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a prospective, phase II, non-randomized clinical imaging trial. Ga68-FAPI-46 is a novel radiotracer used in PET/CT imaging, targeting a protein of the tumor microenvironment called FAP (Fibroblast activation protein). The aim of the study is to assess the accuracy of Ga68-FAPI-46 PET/CT for preoperative assessment of peritoneal carcinomatosis in colorectal and ovarian cancer.
CONDITIONS
Official Title
Ga68-FAPI-46 PET/CT for Preoperative Assessment of Peritoneal Carcinomatosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histologically proven colorectal and ovarian cancer.
- Known or suspected peritoneal metastases from the tumour of origin.
- Scheduled for peritoneal complete cytoreductive surgery with curative intent with or without neoadjuvant chemotherapy.
- ECOG Performance status 2.
- Signed written informed consent obtained before any study-specific screening procedures.
You will not qualify if you...
- Non-resectable extra-abdominal metastasis and/or more than 3 hepatic metastases on standard work-up.
- Known chronic inflammatory conditions including the intestinal system (eg. inflammatory bowel disease, Crohn's disease).
- Pregnant and lactating women.
- Previous or concurrent malignancy diagnosed within the last 3 years except adequately treated in situ carcinoma of the cervix uteri and basal or squamous cell skin cancer.
- Subjects with another significant medical condition which, in the investigator's opinion, may interfere with the completion of the study.
AI-Screening
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Trial Site Locations
Total: 1 location
1
Institut Jules Bordet
Brussels, Belgium
Actively Recruiting
Research Team
L
Loubna Taraji Schiltz
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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