Actively Recruiting

Phase 2
Phase 3
Age: 0 - 17Years
All Genders
NCT04724252

Gabapentin to Reduce Opioid Use Postoperatively (GROUP) in Children

Led by University of California, Davis · Updated on 2025-10-31

60

Participants Needed

1

Research Sites

279 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The primary objective of this study is to determine if the peri and post operative use of gabapentin in children reduces the need for narcotics after thoracic surgery. We hypothesize that patients who are given gabapentin will need fewer morphine equivalents postoperatively than those who were not given gabapentin

CONDITIONS

Official Title

Gabapentin to Reduce Opioid Use Postoperatively (GROUP) in Children

Who Can Participate

Age: 0 - 17Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age newborn to less than 18 years
  • Gestational age of at least 38 weeks
  • Undergoing cardiac surgery via sternotomy or thoracotomy, or any thoracic surgery including planned noncardiac thoracotomy or video-assisted thoracoscopic surgery (VATS)
  • Surgery expected to require at least a 48-hour hospital stay
Not Eligible

You will not qualify if you...

  • Use of opioids within 30 days before the study
  • Renal failure defined by RIFLE criteria
  • History of seizures requiring active treatment
  • History of medically treated chronic pain
  • Diagnosis of autism
  • Unable to tolerate medications given by mouth
  • Hematology or oncology patients
  • Parents or legal guardians unable to provide consent
  • Participation in another clinical study currently or within the last 30 days
  • Pregnancy
  • Prisoner status
  • Undergoing Nuss procedure with cryoablation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UC Davis Medical Center

Sacramento, California, United States, 95817

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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