Actively Recruiting
Gait Analysis in Neurological Disease
Led by Beth Israel Deaconess Medical Center · Updated on 2025-06-08
120
Participants Needed
1
Research Sites
537 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to investigate whether speed-dependent measures of gait can be identified in patients with neurological conditions that affect gait, particularly in subjects with parkinsonian disorders.
CONDITIONS
Official Title
Gait Analysis in Neurological Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 85 years for both healthy and affected subjects
- Presence of at least two of the following in affected subjects: bradykinesia, rest tremor, rigidity, postural instability (UK PD Brain Bank Criteria)
- Montreal Cognitive Assessment used to assess need for legally authorized representative consent; subjects with score ≤ 21 require assent and legal representative consent (affected subjects only)
- Includes subjects with uncertain parkinsonism diagnosis, such as idiopathic Parkinson's Disease or atypical parkinsonisms like Vascular Parkinsonism, Multiple System Atrophy, Progressive Supranuclear Palsy, Normal Pressure Hydrocephalus, or Corticobasal Degeneration (affected subjects only)
- Subjects using assistive walking devices are eligible and may use them during the study (affected subjects only)
- Healthy subjects must have no complaints of difficulty walking, such as arthritic pain, fatigue, or slowness of walking
You will not qualify if you...
- Alternative causes for parkinsonism such as head trauma or drug-induced parkinsonism (affected subjects only)
- Currently treated for a major medical illness requiring hospitalization within the past 14 days (both healthy and affected subjects)
- Currently enrolled in another clinical study with an intervention arm (both healthy and affected subjects)
- Unable to consent due to cognitive impairment without a legally authorized representative (both healthy and affected subjects)
- Cardiac or pulmonary conditions limiting safe participation in walking trials, including congestive heart failure requiring hospitalization in past 90 days, recent myocardial infarction under 90 days, or need for supplemental oxygen due to heart or lung disease (both healthy and affected subjects)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Clinical Research Center BIDMC
Boston, Massachusetts, United States, 02215
Actively Recruiting
Research Team
V
Veronique Vanderhorst, MD PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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