Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID06941155

A Randomized Controlled Trial on Mobile-Based Gamified Combined Cognitive Bias Modification for OCD Symptoms, Obsessive Beliefs, Cognitive Biases, and Psychological Distress in Adults

Led by Dokuz Eylul University · Updated on 2025-05-15

90

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

D

Dokuz Eylul University

Lead Sponsor

T

The Scientific and Technological Research Council of Turkey

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating the effects of a mobile-based gamified combined cognitive bias modification (CBM-C) intervention on adults diagnosed with obsessive-compulsive disorder (OCD). The study aims to compare this gamified intervention with a standard CBM-C and a placebo control to see how they affect OCD symptoms, obsessive beliefs, cognitive biases, depressive symptoms, and psychological distress. This research is important as it explores a new digital approach to treating OCD, which may improve motivation and participation in therapy. Participants will be randomly assigned to one of three groups: a gamified CBM-C, a standard CBM-C, or a placebo control. Each intervention consists of eight sessions over four weeks, delivered twice weekly via a mobile phone app. The gamified CBM-C includes attention and interpretation bias tasks with game-like features to increase engagement, while the standard version has the same tasks without gamification. The placebo condition follows the same structure but lacks active bias modification components. During the study, participants will complete self-report assessments and behavioral tasks at the start, after the four-week intervention, and again at a three-month follow-up. Cognitive biases will be measured using tasks such as the dot-probe with eye-tracking and recognition scenarios. Researchers will track changes in OCD symptoms using several scales, including the Yale-Brown Obsessive Compulsive Scale. This approach will help assess the intervention's impact on symptoms, cognitive biases, and psychological distress over time.

CONDITIONS

Brief Title

Gamified Combined Cognitive Bias Modification in Adults Diagnosed With OCD: Randomized Controlled Trial

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Primary diagnosis of obsessive-compulsive disorder (OCD) confirmed by a licensed clinician using the Structured Clinical Interview for DSM-5 (SCID-5)
  • No current suicidal ideation or psychotic symptoms
  • Access to the internet and a mobile phone
  • Stable psychiatric medication use for at least one month prior to enrollment, with no changes in dosage during the 4-week intervention period
  • No current neurological or medical condition that would interfere with participation
  • Ability to perceive colored visual stimuli (e.g., no color blindness)
  • Not currently enrolled in another intervention-based study
  • Not receiving any other form of psychological treatment at the time of participation
Not Eligible

You will not qualify if you...

  • Presence of active suicidal ideation or psychotic symptoms
  • Unstable psychiatric medication use (e.g., recent dose change within the past month or expected change during the intervention period)
  • Significant neurological or medical illness that may interfere with participation
  • Visual impairments that would prevent accurate perception of colored stimuli (e.g., color blindness)
  • Current participation in another clinical trial involving psychological intervention
  • Receiving concurrent psychotherapy or other psychological treatments outside of the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 4 weeks

Participants receive one of three versions of the combined cognitive bias modification (CBM-C) intervention via mobile phone. The intervention includes attention and interpretation bias modification tasks delivered in eight sessions over four weeks (two sessions per week). The gamified version includes motivational elements, while the standard and placebo versions do not.

8 sessions delivered via mobile phone over 4 weeks (2 sessions per week)

Follow-up

Duration - 3 months

Participants complete assessments to evaluate the lasting effects of the intervention on OCD symptoms, cognitive biases, and psychological distress three months after treatment completion.

1 follow-up assessment

Trial Site Locations

Total: 1 location

1

Dokuz Eylul University Hospital

Izmir, Turkey (Türkiye), 35340

Actively Recruiting

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Research Team

S

Sıla Derin, PhD

O

Orçun Yorulmaz, Prof. Dr.

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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