Actively Recruiting

Age: 18Years - 90Years
All Genders
NCT06666049

Gastric POCUS for Airway Management in Patients Using Glucagon-like Peptide-1 Receptor Agonist (Multicentric)

Led by Clinica Universidad de Navarra, Universidad de Navarra · Updated on 2026-05-05

39

Participants Needed

2

Research Sites

110 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

1\. Introduction Scheduled surgery requires patients to undergo a preoperative fasting period of at least 6 hours to reduce the risk of perioperative pulmonary aspiration. However, certain medications and conditions may delay gastric emptying, potentially increasing aspiration risk. These include diabetic gastroparesis and the use of glucagon-like peptide-1 (GLP-1) receptor agonists for the treatment of diabetes and obesity. GLP-1 receptor agonists are widely used due to their beneficial effects on glycemic control and weight reduction. However, one of their known effects is delayed gastric emptying, which may result in increased residual gastric content despite adherence to standard fasting guidelines. Recent reports have described cases of pulmonary aspiration during anesthesia in patients receiving GLP-1 receptor agonists, even after appropriate fasting. Given the increasing use of these medications, there is a need for objective assessment tools to evaluate gastric content in the perioperative setting. Gastric ultrasonography has emerged as a non-invasive bedside technique that may help identify patients at increased risk of aspiration and guide airway management strategies.

CONDITIONS

Official Title

Gastric POCUS for Airway Management in Patients Using Glucagon-like Peptide-1 Receptor Agonist (Multicentric)

Who Can Participate

Age: 18Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients aged 18 to 90 years
  • ASA physical status I to III
  • Currently treated with GLP-1 receptor agonist medications
  • Scheduled for surgery after fasting for 6 to 8 hours
  • Able to provide informed consent
Not Eligible

You will not qualify if you...

  • History of esophagogastric disease or previous upper abdominal surgery
  • Hiatal hernia or gastroesophageal reflux disease
  • Autonomic nervous system disorders
  • Neurological or neuromuscular diseases
  • Use of medications affecting gastric emptying such as opioids or prokinetics
  • Pregnancy
  • Presence of clinically significant arrhythmias

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Clinica Universidad Navarra

Madrid, Madrid, Spain, 28027

Actively Recruiting

2

CAUSA Salamanca

Salamanca, Spain

Actively Recruiting

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Research Team

C

Carlos Puga Carrasco, MD

CONTACT

M

Miguel Angel Fernandez-Vaquero, MD,PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Gastric POCUS for Airway Management in Patients Using Glucagon-like Peptide-1 Receptor Agonist (Multicentric) | DecenTrialz