Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT04945473

Gastric Recalibration After Endoscopic Sleeve Gastroplasty

Led by IHU Strasbourg · Updated on 2025-05-01

100

Participants Needed

1

Research Sites

268 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Endoscopic sleeve gastroplasty (ESG) is a technique used for bariatric surgery, with results comparable to conventional surgery, in order to treat morbid obesity. It has also less risks of complications, and it is not an irreversible technique. It can be repeated overtime, regarding the evolution of the gastroplasty. There is little data in the literature on the effectiveness of endoscopic "revision". This study will assess the benefits and costs of a revision during the follow-up endoscopy.

CONDITIONS

Official Title

Gastric Recalibration After Endoscopic Sleeve Gastroplasty

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 to 75
  • Patients with morbid obesity (BMI60 30 with comorbidities or > 40)
  • Patients with obesity for more than 2 years
  • Failure of medical treatment of obesity
  • Patients who may benefit from general anaesthesia
  • Patient able to participate in all aspects of the study and that agree to comply with all study requirements, for the duration of the study. This includes the availability of reliable transportation and sufficient time to attend all follow-up visits.
  • Patient able to fully understand the study and ready to give consent to participate to the study.
  • Patient affiliated to the French social security system
Not Eligible

You will not qualify if you...

  • Patient with a contraindication to perform an ESG
  • Patient with a history of previous bariatric, gastric or esophageal surgery.
  • Patient who initiated medical therapy within the last 3 months, with evidence of weight gain.
  • Patient with an uncontrolled, poorly controlled, or suspected history of eating disorders or psychiatric illness.
  • Patient with unstable and precarious state of health, as determined and assessed by the investigator.
  • Patient who is pregnant, breastfeeding or of childbearing age and without effective contraception.
  • Patient in exclusion period (determined by a previous or ongoing study)
  • Patient under legal protection
  • Patient under guardianship or curatorship
  • Patients with a BMI less than 30 at 6 months after ESG. These patients will not be candidate for revision regardless of the randomization group.
  • Patients with a contraindication to MRI may be included in the study and will follow the "No Imaging" study design.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Service de chirurgie digestive et endocrinienne, NHC

Strasbourg, France, 67000

Actively Recruiting

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Research Team

P

Pierre GOEPFERT

CONTACT

A

Armelle TAKEDA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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Gastric Recalibration After Endoscopic Sleeve Gastroplasty | DecenTrialz