Actively Recruiting
Gastrocnemius Myofascial Release in Females With Knee Osteoarthritis
Led by Cairo University · Updated on 2026-04-02
30
Participants Needed
1
Research Sites
38 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to determine whether gastrocnemius myofascial release is effective in reducing pain and improving physical function in females with knee osteoarthritis. The main question this study aims to answer are: * Does adding gastrocnemius MFR to conventional physical therapy treatment influence pain, physical function, foot posture, and knee disability compared to conventional physical therapy treatment and sham MFR in knee osteoarthritis? * Participants receive gastrocnemius myofascial release treatment or sham gastrocnemius myofascial release treatment for 3 times weekly for 4 weeks for both groups.
CONDITIONS
Official Title
Gastrocnemius Myofascial Release in Females With Knee Osteoarthritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female patients aged 45 to 55 years
- Body mass index (BMI) of 35 or less
- Diagnosis of primary knee osteoarthritis according to American College of Rheumatology criteria
- Symptomatic knee osteoarthritis lasting 3 months or more
- Kellgren and Lawrence grade II or III osteoarthritis in the affected knee
- Presence of at least one active trigger point in the gastrocnemius muscle
- If both knees are affected, the more symptomatic knee is selected
- Current knee pain intensity of 4 or higher on the Visual Analogue Scale
- Sufficient cognitive ability to understand and comply with study procedures
- Diagnosis confirmed by knee pain plus osteophytes on X-ray, and at least one of: age over 50, morning stiffness less than 30 minutes, or crepitus on motion
You will not qualify if you...
- Previous knee surgeries or lower limb fractures
- Chronic inflammatory diseases such as rheumatoid arthritis
- Signs of moderate knee synovitis, including warmth, swelling, or redness
- Clinical signs of knee internal derangement (e.g., positive Thessaly test)
- Pregnancy
- Arthroscopy or intra-articular hyaluronic acid treatment within the past 6 months
- Use of NSAIDs within one week before screening
- Orthopedic diseases, congenital musculoskeletal deformities, or neurological disorders affecting treatment
- Participation in other knee osteoarthritis intervention studies or strength training in the past 6 months
- Regular use of psychotropic or narcotic analgesics for at least one week within 8 weeks before screening
AI-Screening
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Trial Site Locations
Total: 1 location
1
Faculty of Physical Therapy, Cairo University
Giza, Giza Governorate, Egypt, 12613
Actively Recruiting
Research Team
H
Hend Hammam Soliman, Bachelor's Degree
CONTACT
A
Afaf Omar Tahoon
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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