Actively Recruiting
Gastroparesis Registry 4
Led by Johns Hopkins Bloomberg School of Public Health · Updated on 2026-04-03
250
Participants Needed
6
Research Sites
136 weeks
Total Duration
On this page
Sponsors
J
Johns Hopkins Bloomberg School of Public Health
Lead Sponsor
T
Texas Tech University Health Sciences Center, El Paso
Collaborating Sponsor
AI-Summary
What this Trial Is About
The Gastroparesis Registry 4 (GpR4) is an observational study of patients with symptoms of gastroparesis (Gp) and functional dyspepsia (FD) with either delayed or normal gastric emptying. To better understand these disorders, this registry will capture demographic, clinical, physiological, questionnaire, and patient outcome data to characterize the patients and their clinical course. Participants will complete several questionnaires, complete a nutrient drink test and have a gastric emptying study.
CONDITIONS
Official Title
Gastroparesis Registry 4
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age at least 18 years at initial screening visit
- Symptoms of gastroparesis and/or functional dyspepsia lasting at least 12 weeks with nausea, vomiting, early satiety, postprandial fullness, abdominal pain, or burning
- Completion of gastric emptying scintigraphy of solids using the 4-hour Egg Beaters® protocol or similar liquid egg white meal within the last 9 months
- Negative upper endoscopy or upper radiographic gastrointestinal series within 5 years of registration
You will not qualify if you...
- Use of narcotic analgesics more than three days per week
- Presence of other conditions explaining symptoms such as pyloric or intestinal obstruction, active inflammatory bowel disease, eosinophilic gastroenteritis or esophagitis
- Primary neurological conditions causing nausea and vomiting like increased intracranial pressure or lesions
- Acute or chronic renal failure with serum creatinine over 3 mg/dL or on dialysis
- Acute liver failure or advanced liver disease (Child's B or C, CPT score ≥7)
- Pancreatic disorders detected by imaging or function tests
- Prior gastric surgery including total or subtotal gastric resection, esophagectomy, gastrojejunostomy, gastric bypass, gastric sleeve, pyloroplasty, pyloromyotomy, or fundoplication
- Any other condition that could explain symptoms or interfere with the study
- Females who are pregnant
- Inability to complete the gastric emptying scintigraphy test (including egg allergy)
- Inability to give informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 6 locations
1
Jay Pasricha
Scottsdale, Arizona, United States, 85259
Actively Recruiting
2
University of Louisville
Louisville, Kentucky, United States, 40202
Actively Recruiting
3
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Actively Recruiting
4
Wake Forest University and Atrium Health Carolinas Medical Center
Charlotte, North Carolina, United States, 28202
Actively Recruiting
5
Temple University Hospital
Philadelphia, Pennsylvania, United States, 19140
Actively Recruiting
6
Texas Tech University Health Science Center (TTUHSC)
El Paso, Texas, United States, 79905
Actively Recruiting
Research Team
L
Laura Miriel
CONTACT
E
Emily Mitchell, MS, MBA
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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