Actively Recruiting

All Genders
NCT03240653

Gaucherite - A Study to Stratify Gaucher Disease

Led by Cambridge University Hospitals NHS Foundation Trust · Updated on 2024-08-06

250

Participants Needed

8

Research Sites

782 weeks

Total Duration

On this page

Sponsors

C

Cambridge University Hospitals NHS Foundation Trust

Lead Sponsor

M

Medical Research Council

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this research is to review data already collected and to collect new data from adults and children in England with Gaucher Disease to determine clinical factors which predict severity and response to therapy of Gaucher disease especially in the areas of bone, cancer and brain conditions.

CONDITIONS

Official Title

Gaucherite - A Study to Stratify Gaucher Disease

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Confirmed biochemical diagnosis of Type I, Type II or Type III Gaucher disease
  • Written Ethics Committee approved informed consent obtained from the patient, or patient's parent or legal guardian and patient assent if appropriate
  • Male or Female patients, no age limitation
  • Willing and able to comply with study schedule and procedures
  • Deceased patients for whom the Ethics Committee determines that patient data can be collected without a new consent from the patient
Not Eligible

You will not qualify if you...

  • Presence of unrelated co-morbid condition limiting life expectancy to less than 6 months
  • Patient or if applicable, parent or legal guardian is unable to comprehend, sign and date the Ethics Committee approved informed consent form and patient assent as appropriate
  • Patients deemed unsuitable for the study by the investigator

AI-Screening

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Trial Site Locations

Total: 8 locations

1

Birmingham Childrens Hospital

Birmingham, United Kingdom

Terminated

2

New Queen Elizabeth Hospital

Birmingham, United Kingdom

Actively Recruiting

3

Cambridge University Hospital

Cambridge, United Kingdom

Actively Recruiting

4

Great Ormond Street Hospital

London, United Kingdom

Actively Recruiting

5

National Hospital for Neurology and Neurosurgery

London, United Kingdom

Actively Recruiting

6

Royal Free Hospital

London, United Kingdom

Actively Recruiting

7

Royal Manchester Childrens Hospital

Manchester, United Kingdom

Actively Recruiting

8

Salford Royal NHS Foundation Trust

Salford, United Kingdom

Actively Recruiting

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Research Team

E

Elizabeth M MORRIS, RN

CONTACT

C

Chong Y TAN, MB PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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