Actively Recruiting
Gauging Outcomes of Total Milk Ingestion on Lipid and gControl
Led by University of California, San Francisco · Updated on 2025-10-24
100
Participants Needed
1
Research Sites
105 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Atherosclerotic cardiovascular disease remains the leading cause of death for adults in the United States. The cardiovascular impact of milk consumption remains a matter of long-standing scientific debate. Current guidelines for Americans recommend three daily servings of fat-free or low-fat (1%) dairy over full-fat options due to concerns that saturated fat may increase cardiovascular risk. Yet, the literature does not consistently support non-fat dairy as superior to high-fat dairy for reducing cardiometabolic risk. Identifying the comparative health benefits of non-fat versus high-fat dairy milk would be immediately applicable to patients who seek cardiovascular care. In this randomized, case-crossover trial, the investigators seek to efficiently assess the association between high-fat versus non-fat dairy milk consumption and insulin resistance. Utilizing the Eureka Platform, participants will be randomized to limit their liquid milk consumption to whole milk followed by skim milk (or vice versa), measuring the effect of milk fat content on glycemic index and lipid profile.
CONDITIONS
Official Title
Gauging Outcomes of Total Milk Ingestion on Lipid and gControl
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Are age 6518 years
- Have a smartphone
- Are able to use the Eureka mobile application
- Consume, on average, at least one cup of dairy milk daily, at least 5 days per week
You will not qualify if you...
- Non-English speaker
- Are lactose intolerant
- History of myocardial infarction
- History of type I or type II diabetes
- Familial hypercholesterolemia
- Plan to change treatment for cholesterol
- Unable to read or sign to provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UCSF Medical Center at Parnassus
San Francisco, California, United States, 94143
Actively Recruiting
Research Team
G
Gregory M Marcus, MD, MAS
CONTACT
B
Bella Peña
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
PREVENTION
Number of Arms
2
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