Personalized Lung Tumor and Organ Motion Tracking Using 4D MRI and 4D CT During Radiation Therapy

What this Trial Is About

Researchers are evaluating a new method to track the movement of lung tumors and nearby organs during radiation treatment for patients with lung cancer. This study focuses on using a four-dimensional magnetic resonance imaging MRI scan before starting radiation and x-ray fluoroscopy images taken during radiation to improve tracking accuracy compared to standard methods. The purpose is to support better targeting during treatment and reduce exposure to healthy tissues. Participants will first receive a baseline 4D CT simulation, which is the current standard care, along with a 4D MRI combined with surface monitoring using a special vest device called EndoScout. During their radiation therapy, patients will undergo additional fluoroscopy imaging and continuous surface monitoring to capture real-time tumor motion. Throughout the study, participants will be closely monitored through imaging and surface tracking during their radiation treatment. Researchers will assess whether this new imaging combination improves the location accuracy of tumors and critical organs over three years. The total involvement includes multiple imaging sessions alongside usual radiation therapy, with safety monitored throughout the process.

GCC 2546- Motion Management