Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07386340

Gemini Study: A Prospective, Multicenter Evaluation of Performance and Safety of the Eversense Gemini System With Flash Glucose Measurement Feature

Led by Senseonics, Inc. · Updated on 2026-04-21

80

Participants Needed

1

Research Sites

122 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

A prospective, multicenter evaluation of performance and safety of the Eversense Gemini System with flash glucose measurement feature. The purpose of this clinical investigation is to evaluate the accuracy of the Gemini System with new technological flash glucose monitoring (FGM) feature enhancements compared to reference glucose measurements and the Eversense 365 CGM System. The investigation will also evaluate safety of the Gemini System usage.

CONDITIONS

Official Title

Gemini Study: A Prospective, Multicenter Evaluation of Performance and Safety of the Eversense Gemini System With Flash Glucose Measurement Feature

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Clinically confirmed diagnosis of diabetes mellitus for at least 1 year
  • Signed informed consent form and willingness to follow protocol requirements
Not Eligible

You will not qualify if you...

  • History of severe hypoglycemia causing loss of consciousness or seizure in past 6 months
  • History of diabetic ketoacidosis requiring emergency or hospital visit in past 6 months
  • Presence of gastroparesis
  • Female subjects of childbearing potential who are pregnant, lactating, planning pregnancy, or not using birth control
  • Conditions preventing or complicating sensor placement, operation, or removal, including upper extremity deformities or skin conditions
  • Symptomatic coronary artery disease, unstable angina, recent myocardial infarction, transient ischemic attack, stroke, uncontrolled hypertension, current congestive heart failure, or cardiac arrhythmia (except benign PACs and PVCs)
  • Hematocrit below 38% or above 60% at screening
  • History of hepatitis B, hepatitis C, or HIV
  • Current treatment for seizure disorder without neurologist clearance
  • History of adrenal insufficiency
  • Receiving immunosuppressant therapy, chemotherapy, anticoagulant/antithrombotic therapy (except aspirin), topical glucocorticoids over sensor site only, or antibiotics for chronic infection
  • Conditions requiring or likely requiring MRI during study
  • Known allergy to topical/local anesthetics or glucocorticoids
  • Any condition that might prevent study completion or pose safety risks, including psychiatric conditions, substance abuse, or increased hypoglycemia risk
  • Participation in another clinical trial within 2 weeks before screening or planned participation during this study
  • Presence of any other active implanted device as defined by the protocol

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Headlands Research - AMCR Institute

Escondido, California, United States, 92025

Actively Recruiting

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Research Team

M

Maggie Lewis

CONTACT

S

Susan Huynh

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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Gemini Study: A Prospective, Multicenter Evaluation of Performance and Safety of the Eversense Gemini System With Flash Glucose Measurement Feature | DecenTrialz