Actively Recruiting
Gene Expression Changes In Young and Geriatric Skin
Led by Wright State University · Updated on 2025-02-06
24
Participants Needed
1
Research Sites
325 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study does not involve any particular diagnosis. The goal of this research study is to explore the effects of artificial sunlight (ultraviolet B radiation; UVB) on the skin of young adults versus geriatric adults. Sunlight exerts many effects on the body. There is evidence that in response to ultraviolet B radiation (UVB), which are the burning rays of sunlight, young adult skin responds differently than geriatric skin. In fact, researchers feel that this difference in how the skin reacts to UVB is why skin cancers are found in older skin. Researchers believe that a major difference between young adult and geriatric skin is that young skin has a lot of a protein called insulin-like growth factor-1 (IGF-1), whereas geriatric skin has very little. The current study will test how young adult versus geriatric skin responds to UVB, and if geriatric skin treated with an injection of small amount of IGF-1 drug will then act like young skin.
CONDITIONS
Official Title
Gene Expression Changes In Young and Geriatric Skin
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female
- White skin (Fitzpatrick types I and II)
- Age 21-30 years or 65 years and older
- Able to understand the study procedures and risks
You will not qualify if you...
- Known photosensitivity
- Currently taking photosensitizing medications
- Diabetes Mellitus
- History of abnormal scarring
- History of skin infections
- Known allergy to lidocaine local anesthetic
- Pregnancy or nursing
- Other serious health issues
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Wright State Physicians
Fairborn, Ohio, United States, 45324
Actively Recruiting
Research Team
M
Manager, Clinical Research Operations
CONTACT
R
Regulatory Specialist
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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