Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06950515

General Anesthesia vs Conscious Sedation for Radial Endobronchial Ultrasound

Led by Institut universitaire de cardiologie et de pneumologie de Québec, University Laval · Updated on 2026-03-06

306

Participants Needed

1

Research Sites

200 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The endoscopic investigation of lung lesions is experiencing significant growth with the increasing number of lung cancer screening programs. Peripheral endobronchial ultrasound (pEBUS) is the most widely used endoscopic technique in the investigation of peripheral pulmonary lesions (PPL). It is performed in relatively equal proportions under conscious sedation and general anesthesia by interventional pulmonologists throughout the world. Users of conscious sedation justify themselves by the fewer resources consumed and the absence of demonstration of a superior diagnostic yield of general anesthesia while users of general anesthesia claim diagnostic yield and comfort for the patient are superior with their approach. Our main objective is to compare the diagnostic yield of pEBUS under general anesthesia to that obtained under conscious sedation.

CONDITIONS

Official Title

General Anesthesia vs Conscious Sedation for Radial Endobronchial Ultrasound

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older with ability to consent
  • Peripheral lung lesion less than 5 cm in diameter on CT scan
  • Lesion accessible to pEBUS as determined by an experienced interventional pulmonologist
  • Agreement by medical team and patient to use pEBUS for diagnosis of lung lesion
Not Eligible

You will not qualify if you...

  • Use of electromagnetic navigation, augmented fluoroscopy, or robotic bronchoscopy planned in addition to pEBUS
  • Suspicious lymph nodes 10 mm or larger or with moderate or greater hypermetabolism accessible by linear EBUS
  • Contraindications to bronchoscopy or biopsy such as unstable medical condition or uncorrected bleeding risk
  • Current pregnancy
  • Lack of free and informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Institut universitaire de cardiologie et de pneumologie de Québec

Québec, Quebec, Canada, G1V 4G5

Actively Recruiting

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Research Team

M

Marc Fortin, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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