Actively Recruiting

All Genders
NCT06423950

Generating Novel Translational and Therapeutic Strategies Based on a Multicenter, Pediatric and AYA Evolutionary Tumor Board (pedsETB)

Led by H. Lee Moffitt Cancer Center and Research Institute · Updated on 2026-02-09

35

Participants Needed

1

Research Sites

152 weeks

Total Duration

On this page

Sponsors

H

H. Lee Moffitt Cancer Center and Research Institute

Lead Sponsor

N

National Pediatric Cancer Foundation

Collaborating Sponsor

AI-Summary

What this Trial Is About

To evaluate the ability of a multidisciplinary and multisite group, the Pediatric Evolutionary Tumor Board (pedsETB), to develop additional therapeutic strategies in patients without curative options or with suboptimal outcomes.

CONDITIONS

Official Title

Generating Novel Translational and Therapeutic Strategies Based on a Multicenter, Pediatric and AYA Evolutionary Tumor Board (pedsETB)

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participant must be considered likely incurable given the standard of care, including newly diagnosed, relapsed, in remission but at high risk of recurrence, or with suboptimal responses to previous therapy.
  • Age-appropriate performance status: Karnofsky score 50 or more for patients 16 years or older, or Lansky score 50 or more for patients under 16.
  • Participant and/or parents or legal guardian and primary oncologist must be willing to consider therapeutic strategies recommended by the pedsETB.
  • Participant must be willing to be followed over time and allow collection of clinical data including scans, blood and lab samples, with optional serial blood sampling.
  • All participants and/or their parents or legal guardians must understand and be willing to sign a written informed consent or assent document.
Not Eligible

You will not qualify if you...

  • Participants without known therapies to reliably induce a response are excluded and should seek clinical trials.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Moffitt Cancer Center

Tampa, Florida, United States, 33612

Actively Recruiting

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Research Team

J

Jessica Crimella

CONTACT

J

Jonathan Metts, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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