Actively Recruiting
Generation of Endometrial Carcinoma Organoids
Led by Regina Elena Cancer Institute · Updated on 2025-12-02
20
Participants Needed
1
Research Sites
182 weeks
Total Duration
On this page
Sponsors
R
Regina Elena Cancer Institute
Lead Sponsor
A
Azienda Ospedaliera Universitaria Integrata Verona
Collaborating Sponsor
AI-Summary
What this Trial Is About
A prospective pilot genetic study to evaluate the feasibility of generating organoids from endometrial tumor tissue collected during surgery, performed according to standard clinical practice. Samples will be collected from collaborating extramural facilities, with the aim of analyzing the impact of transport on tissue viability and the success of organoid culture. This study is for exploratory purposes only, without altering the diagnostic and therapeutic pathways of the participants.
CONDITIONS
Official Title
Generation of Endometrial Carcinoma Organoids
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age >18 years
- Histological diagnosis of endometrial cancer with endometrioid histology, any stage (FIGO I-IV), including recurrence or metastasis
- Candidates for surgery and/or hysterectomy
- Written informed consent obtained before any study procedures
You will not qualify if you...
- Uncontrolled comorbidities despite medical therapy
- Endometrial cavity infections (pyometra)
- Presence of synchronous tumors
- Receiving neoadjuvant treatments
- Previous radiation therapy to the pelvic region
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
IRCCS National Cancer Institute "Regina Elena"
Roma, Roma, Italy, 00144
Actively Recruiting
Research Team
G
Giovanni Blandino, Medical Doctor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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