Actively Recruiting
Genes and Environment in Multiple Sclerosis
Led by Columbia University · Updated on 2026-05-14
5000
Participants Needed
5
Research Sites
1200 weeks
Total Duration
On this page
Sponsors
C
Columbia University
Lead Sponsor
U
University of Pittsburgh
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of the research study is to identify the genetic, environmental and immune profiles that may increase a person's risk of developing multiple sclerosis (MS). While MS is not a disease caused by a single variation in genetic material (DNA), a single environmental factor, or a single malfunction in immune cells, there are genetic alterations, environmental exposures and immunologic factors that make the development of MS more likely. Obtaining information about who is at risk for MS will be beneficial in the future if the investigators can identify effective ways to prevent or slow down the progression of this disease.
CONDITIONS
Official Title
Genes and Environment in Multiple Sclerosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be a first-degree relative of a patient with multiple sclerosis
- Have received anti-TNFa therapy for inflammatory diseases other than MS such as Crohn's disease, psoriasis, or rheumatoid arthritis
- Have been referred for evaluation of first neurological symptoms but do not have a diagnosis of MS
- Live in the United States
- Be 18 years of age or older
You will not qualify if you...
- Do not meet any of the inclusion criteria
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 5 locations
1
National Institute of Neurological Disorders and Stroke
Bethesda, Maryland, United States, 15213
Actively Recruiting
2
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Terminated
3
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115
Terminated
4
Columbia University Irving Center
New York, New York, United States, 10032
Actively Recruiting
5
University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15213
Actively Recruiting
Research Team
J
Juliana Oyegunle
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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