Actively Recruiting

Age: 18Years - 100Years
All Genders
Healthy Volunteers
NCT05732987

Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases

Led by University Hospital, Basel, Switzerland · Updated on 2023-08-22

3370

Participants Needed

1

Research Sites

343 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is to identify rare, disease-causing mutations of several rare neutrophil dermatoses. To identify associations between NMID and variants in the genome next generation sequencing, mainly whole exome sequencing, will be used. In a second approach the expression level of already known inflammatory proteins in skin samples will be investigated.

CONDITIONS

Official Title

Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases

Who Can Participate

Age: 18Years - 100Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Written consent of the participating person
  • Diagnosis of a disease in the neutrophil-mediated inflammatory dermatoses (NMID) group or being a proband in the control group
Not Eligible

You will not qualify if you...

  • Missing informed consent if samples collected after 2014 (patients)
  • No diagnosis of NMID (patients)
  • Missing informed consent (healthy controls)

AI-Screening

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Trial Site Locations

Total: 1 location

1

University Hospital Basel, Clinic of Dermatology

Basel, Switzerland, 4031

Actively Recruiting

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Research Team

A

Alexander Navarini, Prof. Dr. med.

CONTACT

E

Emmanuel Contassot, Dr.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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