Actively Recruiting
Genetic Basis of Melanocytic Nevi
Led by University of California, Davis · Updated on 2025-09-18
50
Participants Needed
1
Research Sites
570 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The objective of this protocol is to further elucidate the genetic mutations that drive melanocytic nevi (benign melanocytic neoplasms, moles). This will be performed by whole genome, whole exome, or targeted sequencing of de-identified specimens. Herein, the investigators plan to isolate DNA from de-identified skin biopsy specimens and blood samples: 1. From melanocytic nevi collected by skin biopsy (a shave or punch biopsy). A part of the tissue will be submitted for routine diagnostic dermatopathology and investigational histomorphologic and immunohistochemical analysis. 2. From corresponding normal tissue (blood). DNA isolated from blood will be used as a normal control when analyzing sequencing data to identify somatic mutations in lesional tissue.
CONDITIONS
Official Title
Genetic Basis of Melanocytic Nevi
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female subjects that are 18 years or older
- Subjects with melanocytic nevi
You will not qualify if you...
- Patients less than 18 years of age
- Patients without melanocytic nevi
- Patients with a bleeding disorder or are taking anticoagulation medication
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of California-Davis, Department of Dermatology
Sacramento, California, United States, 95816
Actively Recruiting
Research Team
M
Maija Kiuru, MD
CONTACT
J
John Robb
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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