Genetic Study of Arrhythmia-Induced Cardiomyopathy and Its Impact on Heart Health

What this Trial Is About

Researchers are investigating the genetic aspects of arrhythmia-induced cardiomyopathy AiC, a condition where a new arrhythmia causes reduced heart pumping function. This observational study aims to understand whether patients with AiC have more genetic mutations compared to other cardiomyopathy types or the general population, and whether genetics affect the outlook for these patients. The study includes patients suspected of AiC undergoing rhythm control procedures like electric cardioversion or catheter ablation. Participants will be followed for one year after these procedures, with genetic testing conducted to identify variants in genes related to cardiomyopathy. Follow-up visits occur at 2, 6, and 12 months, including electrocardiograms and heart imaging to monitor heart function and remodeling. Participants will have their heart rhythm and left ventricular function evaluated over time to confirm AiC and assess recovery. The study measures the presence of harmful genetic variants, heart failure admissions, arrhythmia recurrence, additional rhythm control procedures, and heart remodeling changes. The research team will observe clinical events and genetic links to the condition during the one-year follow-up period.

Genetic Characterization of Patients With Arrhythmia-Induced Cardiomyopathy