Effects of remote ischemic preconditioning on the coagulation profile of patients with aneurysmal subarachnoid hemorrhage: a case-control study.
Fernando Mayor, Arzu Bilgin-Freiert, Mark Connolly...
https://pubmed.ncbi.nlm.nih.gov/23867300Actively Recruiting
Age: 18Years +
All Genders
ID02910180
Genetic, Metabolic, and Growth Factor Repository for Cerebrovascular Disorders and Stroke Observational Study
Led by Cedars-Sinai Medical Center · Updated on 2023-02-08
900
Participants Needed
1
Research Sites
743 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are creating and maintaining a collection of biological samples from patients with cerebrovascular diseases and stroke. This study aims to use these samples to better understand the causes and effects of these conditions by analyzing genetic, metabolic, and growth factor markers. The study is observational and focuses on building a repository that can support future research into patient outcomes and disease progression. Samples collected include blood, cerebrospinal fluid, tissue, and microdialysis samples. Along with these, detailed patient information such as age, gender, diagnosis, medical and family history, treatments received, radiology reports, and outcomes are recorded and updated during follow-up visits. The repository will help explore how biological factors relate to disease development, treatment response, and prognosis. Participants will be followed over time with clinical data collected at baseline and multiple follow-up points. Researchers will measure changes in functional and cognitive scales such as the modified Rankin Scale, NIH Stroke Scale, Barthel Index, and Montreal Cognitive Assessment test at baseline, 1 month, 3 months, and 6 months. This ongoing data collection aims to track patient progress and link biological markers with clinical outcomes, helping to improve understanding of cerebrovascular disorders.
CONDITIONS
Official Title
Genetic, Metabolic, and Growth Factor Repository for Cerebrovascular Disorders
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
- All patients diagnosed with cerebral vascular disease, regardless of gender, age, ethnicity/race, stage of disease or treatment
- Expected availability of clinical follow-up data
- Willingness to provide written, informed consent according to institutional and federal guidelines
You will not qualify if you...
- Pregnant women are excluded from the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Trial Site Locations
Total: 1 location
1
Cedars-Sinai Medical Center
Los Angeles, California, United States, 90048
Actively Recruiting
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Research Team
N
Nestor R Gonzalez, MD, MSCR
P
Patrick Lyden, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Frequently Asked Questions
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Published Research Related To This Trial
Remote Ischemic Conditioning Alters Methylation and Expression of Cell Cycle Genes in Aneurysmal Subarachnoid Hemorrhage.
Elina Nikkola, Azim Laiwalla, Arthur Ko...
https://pubmed.ncbi.nlm.nih.gov/26251247Angiographic Structural Differentiation between Native Arteriogenesis and Therapeutic Synangiosis in Intracranial Arterial Steno-Occlusive Disease.
Y C Ooi, A N Laiwalla, R Liou...
https://pubmed.ncbi.nlm.nih.gov/26797139Muscle microdialysis to confirm sublethal ischemia in the induction of remote ischemic preconditioning.
Arzu Bilgin-Freiert, Joshua R Dusick, Nathan R Stein...
https://pubmed.ncbi.nlm.nih.gov/24323782