Actively Recruiting
Genetic of Response to Acute Saline Load Test in Hypertension (Naload)
Led by Ospedale San Raffaele · Updated on 2024-05-14
150
Participants Needed
1
Research Sites
325 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
NHP referred to our outpatient clinic will be enrolled (150 newly recruited) in acute saline test for phenotype characterisation of PNat relationship(7). For each patient we will collect urine and blood samples for standard clinical biochemistry, including electrolytes, creatinine, EO, aldosterone, plasma renin activity, urinary uromodulin (ELISA), urinary and serum uric acid and blood samples for genetic test.
CONDITIONS
Official Title
Genetic of Response to Acute Saline Load Test in Hypertension (Naload)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 65 years
- Body mass index (BMI) less than 30 kg/m2
- Sodium intake less than 300 mEq/24 hours based on urinary sodium excretion
- Office systolic blood pressure over 140 mm Hg and diastolic blood pressure over 90 mm Hg measured in 3 consecutive visits to their family doctors
You will not qualify if you...
- Female patients
- History of myocardial infarction
- History of stroke
- History of congestive heart failure
- Liver disease
- Secondary causes of hypertension
- Diabetes
- Severe hypertension with blood pressure over 160/110 mm Hg
- Abuse of drugs or alcohol
- Creatinine clearance less than 80 mL/min
- Secondary forms of hypertension ruled out with specific investigations when appropriate
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
IRCCS Ospedale San Raffaele
Milan, Italy, 20132
Actively Recruiting
Research Team
C
Chiara Lanzani, doctor
CONTACT
C
Cinzia Scotti, secretary
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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