Design of a multicenter randomized clinical trial for chronic prostatitis/chronic pelvic pain syndrome.
Kathleen J Propert, Richard B Alexander, J Curtis Nickel...
https://pubmed.ncbi.nlm.nih.gov/12031372Actively Recruiting
MALE
ID00499317
Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
Led by Boston Children's Hospital · Updated on 2023-08-14
500
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a condition that may have various causes, some of which are unknown, and it is believed that genetic factors might contribute to its development. This research aims to explore whether CP/CPPS has a genetic cause by collecting genetic material and medical information from individuals and families affected by CP/CPPS or related bladder conditions. The study is observational and seeks to better understand symptoms and their genetic links. Participants will provide DNA samples through blood or saliva, urine samples, and complete brief questionnaires. Those affected may also be asked to provide bladder tissue samples from previous clinical biopsies. All collected samples will be stored for analysis. Importantly, participants do not need to travel to Boston for this study. Throughout the study, researchers will gather medical information and genetic material to analyze potential genetic contributions to CP/CPPS. Participants will be involved in giving samples and answering questionnaires. The study includes family members whether or not they have symptoms. The timeline for participation varies, with no specific treatment or intervention administered, as this is an observational study.
CONDITIONS
Brief Title
Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
Who Can Participate
MALE
Eligibility Criteria
You may qualify if you...
- Have symptoms for at least 3 months within the preceding 6 months including pelvic pain, urinary frequency, urgency, or sexual dysfunction
- Diagnosed with CP/CPPS, Interstitial Cystitis, Bladder Pain Syndrome, or Bladder Fasciculation Syndrome
- Willing to provide blood/saliva, bladder tissue (from previous biopsy), and urine samples
- Agree to complete several brief questionnaires
- Family member of someone with CP/CPPS, BPS, IC, or BFS
- Live in the USA or Canada
You will not qualify if you...
- Major structural or anatomical urinary tract abnormalities
- Inborn or congenital conditions affecting the urinary tract
- History of surgery or chemotherapy in the pelvic area
- Bacterial cause of CP/CPPS or recurrent urinary tract infections
- Traumatic cause of CP/CPPS
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person or remote)
Sample Collection
Duration - 1 day
Participants provide blood or saliva, urine samples, and may provide bladder tissue from a previous biopsy. They also complete several brief questionnaires.
1 visit (in-person or remote)
Long-term Monitoring
Duration - Up to study completion
Participants' genetic and symptom data are analyzed to understand chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). No active intervention is provided.
No additional visits required
Trial Site Locations
Total: 1 location
1
Boston Children's Hospital (BCH)
Boston, Massachusetts, United States, 02115
Actively Recruiting
Loading map...
Research Team
E
Elicia Estrella, MS, LCGC
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Published Research Related To This Trial
Abnormal Akt signalling in bladder epithelial cell explants from patients with interstitial cystitis/bladder pain syndrome can be induced by antiproliferative factor treatment of normal bladder cells.
Susan K Keay, Chen-Ou Zhang
https://pubmed.ncbi.nlm.nih.gov/26919663A case of familial clustering of interstitial cystitis and chronic pelvic pain syndrome.
J D Dimitrakov
https://pubmed.ncbi.nlm.nih.gov/11489726