Actively Recruiting

All Genders
Healthy Volunteers
NCT02735824

Genetic Study of Immunodeficiency: Search for New Genetic Causes for Primary Immunodeficiencies

Led by University Children's Hospital, Zurich · Updated on 2026-05-14

500

Participants Needed

1

Research Sites

617 weeks

Total Duration

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AI-Summary

What this Trial Is About

Individuals with suspected primary immunodeficiency will be studied and the results compared with healthy controls. Primary immunodeficiency may manifest as recurrent, severe or unusual infections as well as signs and symptoms of immune dysregulation such as autoimmunity or lymphoproliferation.

CONDITIONS

Official Title

Genetic Study of Immunodeficiency: Search for New Genetic Causes for Primary Immunodeficiencies

Who Can Participate

All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Pediatric patients (inpatient or outpatient or referred) with suspected or confirmed Inborn Errors of Immunity
  • Healthy or affected biological relatives of enrolled patients
  • Healthy volunteers with no history of chronic immunological, inflammatory, or infectious disease
  • Ability to provide signed informed consent or guardian consent
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 1 location

1

Division of Immunology

Zurich, Canton of Zurich, Switzerland, 8008

Actively Recruiting

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Research Team

J

Jana M Pachlopnik Schmid, MD PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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