Actively Recruiting
Genetics in Parkinson's Disease: Behavioral and Cognitive Outcomes
Led by Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico · Updated on 2024-03-26
68
Participants Needed
1
Research Sites
521 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The genetic landscape of Parkinson's disease (PD) is characterised by rare high penetrance pathogenic variants causing familial disease, genetic risk factor variants driving PD risk in a significant minority in PD cases and high frequency, low penetrance variants, which contribute a small increase of the risk of developing sporadic PD. This knowledge has the potential to have a major impact in the clinical care of people with PD. The goal of this observational study is to evaluate the impact of genetic mutation on behavior and cognition in PD patients. Patients will be assessed over time using test, questionnaire and standardised clinica scales. An initial assessment and annual follow-up assessments will be carried out for 5 years. Researchers will compare data collected from patients with genetic mutation versus patients without mutation.
CONDITIONS
Official Title
Genetics in Parkinson's Disease: Behavioral and Cognitive Outcomes
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with Parkinson's Disease (PD)
- Currently using dopaminergic medication (L-Dopa and/or dopamine agonists)
- Have undergone genetic testing for mendelian forms of Parkinson's Disease
- Able to provide informed consent to participate in the study
You will not qualify if you...
- Have undergone Deep Brain Stimulation (DBS) treatment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, Italy, 20122
Actively Recruiting
Research Team
F
Francesca Mameli, Dr
CONTACT
F
Fabiana Ruggiero, Dr
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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