Actively Recruiting
Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau
Led by University of Chicago · Updated on 2026-02-05
38
Participants Needed
1
Research Sites
101 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The investigators are conducting this research study to find better ways of treating pain following knee surgery. There is a standard (accepted) approach, which involves injection of numbing medication into the area around the participant surgical incision. The investigators hope to discover if providing numbing medication to a nerve that controls pain in a larger area of the knee (a nerve block), might be better at post-operative pain control.
CONDITIONS
Official Title
Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years and older
- Undergoing open reduction internal fixation of an acute isolated tibial plateau fracture
You will not qualify if you...
- Younger than 18 years
- Polytraumatized patients
- Pathologic fractures
- Tibial plateau fractures treated nonoperatively
- Re-operations at the same surgical site
- Open fractures
- Fracture-dislocations
- History or active anxiety
- Preoperative visual analog scale anxiety score 7 or higher
- Chronic pain syndromes
- Chronic opioid use
- Illicit drug use disorder
- Alcohol abuse disorder
- Kidney disease preventing use of ketorolac
- Liver disease preventing use of acetaminophen
- Allergy to acetaminophen, NSAIDs, opiates, or local anesthesia
- Inability to provide postoperative visual analog scale pain scores
- Contraindications to peripheral nerve blocks including neurologic deficits or active infection at injection sites
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Chicago
Chicago, Illinois, United States, 60637
Actively Recruiting
Research Team
A
Anthony Christiano, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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