Actively Recruiting
Genicular Nerve Block for Knee Pain in the ED
Led by University of Pennsylvania · Updated on 2026-02-12
34
Participants Needed
4
Research Sites
55 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Patient with atraumatic knee pain without a large knee effusion on x-ray will be randomized to receive either a genicular nerve block (GNB) or standard of care in the emergency department.
CONDITIONS
Official Title
Genicular Nerve Block for Knee Pain in the ED
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Atraumatic knee pain
- X-ray of the knee obtained in the emergency department
- Initial pain score between 5 and 10 on a numeric rating scale
You will not qualify if you...
- Fracture or dislocation seen on knee X-ray
- Large knee joint effusion on X-ray
- Allergy or contraindication to local anesthetics
- History of local anesthetic systemic toxicity
- Pregnancy
- Currently incarcerated
- History of knee replacement on the affected knee
- Concern for septic joint
- Overlying cellulitis
- Hemodynamic instability
- Altered mental status or inability to consent to the procedure
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
2
Pennsylvania Hospital
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
3
Pennsylvania Presbyterian Medical Center
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
4
HUP Cedar
Philadelphia, Pennsylvania, United States, 19143
Actively Recruiting
Research Team
U
Umar Clinical Research Coordinator, AB
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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