Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT06436846

Genomic Risk in Retroperitoneal Sarcoma

Led by Fox Chase Cancer Center · Updated on 2024-05-31

50

Participants Needed

1

Research Sites

281 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The protocol intends to explore the biology which may underlie recurrences of retroperitoneal liposarcoma. Surgery remains the only curative intent intervention for this disease. Often, tumors recur in locations within the retroperitoneum remote from the original primary tumor. This study hypothesizes that normal appearing retroperitoneal fat actually harbors underlying genetic changes which predispose to development of future liposarcoma. To accomplish this goal, retroperitoneal fat is sampled from quadrants within and remote from the primary tumor and is subsequently subjected to genetic analyses looking for such predisposing factors.

CONDITIONS

Official Title

Genomic Risk in Retroperitoneal Sarcoma

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients (age ≥18 years).
  • Histologically confirmed retroperitoneal liposarcoma via preoperative biopsy, or cross-sectional imaging suspicious for liposarcoma with planned surgical resection
  • Will be undergoing surgical resection for treatment of primary or recurrent disease
  • Have provided informed consent to participate in this study
Not Eligible

You will not qualify if you...

• Prior surgical anatomy which makes sampling of remote areas of the retroperitoneum technically impossible or clinically undesirable for safety reasons

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fox Chase Cancer Center

Philadelphia, Pennsylvania, United States, 19111

Actively Recruiting

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Research Team

A

Anthony Villano, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Genomic Risk in Retroperitoneal Sarcoma | DecenTrialz