Actively Recruiting

Age: 5Years - 99Years
All Genders
Healthy Volunteers
NCT05212792

Genomics and COVID-19 Vaccine Adverse Events

Led by University of British Columbia · Updated on 2026-05-01

6325

Participants Needed

1

Research Sites

231 weeks

Total Duration

On this page

Sponsors

U

University of British Columbia

Lead Sponsor

C

Centers for Disease Control and Prevention

Collaborating Sponsor

AI-Summary

What this Trial Is About

Vaccines routinely used are extremely safe; however, severe adverse events to vaccines do occur. As vaccination against COVID-19 has begun, adverse events to the vaccine, particularly Guillain-Barré syndrome (GBS), vaccine-induced immune thrombotic thrombocytopenia (VITT)/thrombosis with thrombocytopenia syndrome (TTS), and myocarditis/pericarditis, after COVID-19 vaccination have been reported worldwide. Study hypothesis: there are genetic factors that contribute to increased risks of particular COVID-19 vaccine-induced adverse events. The objective of the study is to determine if there are specific genetic factors strongly associated with each of the COVID-19 vaccine-induced adverse events (i.e., GBS, VITT/TTS, and myocarditis/pericarditis).

CONDITIONS

Official Title

Genomics and COVID-19 Vaccine Adverse Events

Who Can Participate

Age: 5Years - 99Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients who received COVID-19 vaccines and developed Guillain-Barr�e9 syndrome (GBS), vaccine-induced immune thrombotic thrombocytopenia (VITT)/thrombosis with thrombocytopenia syndrome (TTS), or myocarditis/pericarditis after vaccination
  • Participants who received COVID-19 vaccines and did not experience GBS, VITT/TTS, or myocarditis/pericarditis
Not Eligible

You will not qualify if you...

  • Individuals who have not received a COVID-19 vaccine
  • Individuals unable to provide informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

British Columbia Children's Hospital Research Institute

Vancouver, British Columbia, Canada, V5Z 4H4

Actively Recruiting

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Research Team

B

Bruce Carleton, PharmD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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