Actively Recruiting

Age: 60Years +
All Genders
NCT03713853

Geriatric Acetabular fracTures: Open Reduction Internal Fixation Versus Replacement

Led by Unity Health Toronto · Updated on 2025-12-24

104

Participants Needed

1

Research Sites

260 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Management of acetabular (hip) fractures in the geriatric population can be very challenging because of pre-existing medical comorbidities, pre-existing osteoporosis and increased risk of mortality. The two most common treatment options for acetabular fractures are either surgical fixation using plates and screws to hold the fractured pieces in the correct position until the fracture has healed or surgical fixation in addition to a total hip replacement. Surgical fixation requires prolonged immobilization of the affected limb (typically around 6-12 weeks post-operatively), which can lead to disability and other complications. Such patients, especially those who are frail and cognitively impaired, are unable to adhere to the immobilization restrictions, leading to an increased risk of fixation failure. Patients who underwent open reduction internal fixation (ORIF) of an acetabular fracture were reported to have about 25 times greater incidence of hip replacement compared with general population matched controls. Additionally, performing a subsequent hip replacement after a previous surgical fixation (ORIF) of an acetabular fracture, especially in the elderly population, can present a number of technical difficulties including; difficult dissection due to previous incision(s) and scarring, dealing with retained hardware, bony deficiency and the possibility of infected hardware. The aim of the study is to perform a large cohort study to assess pain and physical function in patients 60 years and older who have sustained an acetabular fracture.

CONDITIONS

Official Title

Geriatric Acetabular fracTures: Open Reduction Internal Fixation Versus Replacement

Who Can Participate

Age: 60Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 60 years of age or older
  • Isolated and displaced acetabular fracture (2 mm or more displacement on any X-ray view)
  • Fracture requires surgical treatment with either ORIF alone or ORIF plus total hip arthroplasty
  • Fracture is acute, within 3 weeks of injury
  • Patient was ambulatory before the fracture, with or without walking aids
  • Patient can provide informed consent
  • Patient can read and understand English
Not Eligible

You will not qualify if you...

  • Active or chronic infection around the fracture (soft tissue or bone)
  • Open or compound fracture
  • Bilateral acetabular fractures
  • Pathological fracture excluding osteoporosis
  • Periprosthetic fracture (previous arthroplasty, hardware, or ORIF in place)
  • Medical or surgical reasons preventing surgery
  • Dementia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Unity Health Toronto - St Michael's Hospital

Toronto, Ontario, Canada, M5C 1R6

Actively Recruiting

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Research Team

C

Cassandra Tardif-Theriault, BKin

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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