Actively Recruiting
Geriatric Assessment and Management for Older Adults Undergoing Chemotherapy and Radiation Therapy for Head and Neck Cancer and Their Family Caregivers
Led by City of Hope Medical Center · Updated on 2026-05-11
36
Participants Needed
1
Research Sites
71 weeks
Total Duration
On this page
Sponsors
C
City of Hope Medical Center
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This clinical trial compares the effect of geriatric assessment (GA)-based management of supportive care to usual care in treating older patients undergoing chemotherapy and radiation therapy for head and neck cancer and their family caregivers (FCG). At least one quarter of head and neck cancers patients are diagnosed at age 70 or older. Treatment for head and neck cancers usually include surgery, chemotherapy, and radiation. Older adults are often at higher risk for functional problems, and may experience more side effects. In addition, there may be a lack of support mechanisms in place to address the needs of these older patients. Cancer not only affects the patients but the entire family, especially the family member who is the caregiver. Currently, all patients over 65 receive the same standard of care based on national guidelines, which include supportive care referrals. However, data suggests, that many patients may need more frequent and structured support. The Practical Geriatric Assessment (PGA) is a complete examination including evaluation of the physical and mental function as well as the emotional state of the older patient. PGA-based supportive care interventions may be safe, tolerable, and/or effective in managing treatment-related side effects and improving quality of life compared to usual care in older patients undergoing chemotherapy and radiation therapy for head and neck cancer and their FCG.
CONDITIONS
Official Title
Geriatric Assessment and Management for Older Adults Undergoing Chemotherapy and Radiation Therapy for Head and Neck Cancer and Their Family Caregivers
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Documented written informed consent
- Diagnosis of non-metastatic head and neck cancer
- Age 60 years or older
- Scheduled to undergo curative-intent definitive radiation with or without concurrent chemotherapy or postoperative radiation with or without concurrent chemotherapy
- Must have at least one geriatric assessment as assessed by the modified Geriatric 8 (G8) tool
- Family caregivers are encouraged to participate but not required; caregivers will be randomized with their patients
- Ability to read and understand English
- Caregivers must be family or friends involved in the patient's medical care
- Caregivers must be 18 years or older
You will not qualify if you...
- Not explicitly stated in the provided eligibility criteria
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Trial Site Locations
Total: 1 location
1
City of Hope Medical Center
Duarte, California, United States, 91010
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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