Actively Recruiting

Age: 18Minutes +
MALE
NCT06215508

Geriatric Assessment and Technology Evaluation in Prostate Cancer

Led by University of Chicago · Updated on 2025-06-08

120

Participants Needed

1

Research Sites

260 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

By doing this study, doctors hope to learn more about factors that contribute to frailty (a condition where older adults feel weak, get tired easily, and struggle more with everyday activities) and serious side effects among men over the age of 65 who will receive androgen deprivation therapy (also called "hormone therapy") for prostate cancer that has spread to other parts of their body. Participation in this research will last about 5 years. For the first year, participants will have 5 study visits where they have give blood samples, answer survey questions, and use a wearable device. After study visits are complete, there is a 4-year follow-up period. Research team will check regular doctor visits and look at participants' medical records.

CONDITIONS

Official Title

Geriatric Assessment and Technology Evaluation in Prostate Cancer

Who Can Participate

Age: 18Minutes +
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Male patients with confirmed adenocarcinoma of the prostate without certain rare cell types
  • Must have at least one metastatic lesion confirmed by scans or molecular imaging
  • Age 65 years or older
  • Planned to start intensified hormone therapy including androgen deprivation therapy and androgen receptor signaling inhibitor
  • Able to understand and willing to sign informed consent
Not Eligible

You will not qualify if you...

  • Previous exposure to androgen deprivation therapy or androgen receptor signaling inhibitor within 12 months, except starting within 12 weeks prior to enrollment
  • Surgical orchiectomy performed more than 12 weeks before metastatic diagnosis
  • Previous chemotherapy for metastatic prostate cancer
  • Having uncontrolled medical illnesses that are not well managed or stable
  • Diagnosis of small-cell carcinoma of the prostate or brain metastasis
  • Not fluent in reading or writing English or Spanish
  • Female or pregnant women excluded
  • Presence of implantable cardiac devices
  • Limb defects that prevent wearing a smartwatch

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

o University of Chicago Medicine Comprehensive Cancer Center

Chicago, Illinois, United States, 60637

Actively Recruiting

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Research Team

C

Clinical Trials Intake

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Geriatric Assessment and Technology Evaluation in Prostate Cancer | DecenTrialz