Actively Recruiting

Age: 18Years - 100Years
All Genders
ID04681690

German National Registry for Nephron-Sparing Surgery for Localized Kidney Tumors

Led by Association of Urologic Oncology (AUO) · Updated on 2025-01-29

1000

Participants Needed

5

Research Sites

52 weeks

Total Duration

On this page

Sponsors

A

Association of Urologic Oncology (AUO)

Lead Sponsor

I

IAG-N at German Cancer Association (Deutsche Krebsgesellschaft e. V.)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are collecting data from patients undergoing partial nephrectomy, a kidney-sparing surgery, to treat localized kidney tumors. This observational registry study aims to identify key factors that influence the quality of surgical care by gathering detailed clinical and outcome information. The study focuses on understanding outcomes related to different surgical approaches, including open and minimally-invasive techniques like robotic surgery, which is increasingly used for complex tumors. Participants in this study undergo nephron-sparing surgery for localized renal masses, and their clinical data is recorded in the G-NeSS registry. The data collected includes patient details, tumor location and complexity, surgical approach, complications during and after surgery, and kidney function. Follow-up questionnaires are conducted at 30 days, 12 months, 24 months, and 60 months to monitor long-term kidney function, comorbidities, and survival. During the study, participants will have their clinical and surgical information recorded, with regular follow-ups to assess outcomes such as complication rates, kidney function measured by glomerular filtration rate, and survival over 60 months. This comprehensive monitoring helps researchers understand the long-term effects of partial nephrectomy and improve surgical care for patients with kidney tumors. Participation may last up to five years with these scheduled assessments.

CONDITIONS

Brief Title

German National Registry for NSS

Who Can Participate

Age: 18Years - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Written informed consent
  • Localized kidney tumor suitable for nephron-sparing surgery
  • Adequate abdominal imaging with contrast-enhanced CT or MRI
Not Eligible

You will not qualify if you...

  • Diagnosis or suspicion of urothelial cancer of the kidney
  • Prior nephron-sparing surgery on the same kidney
  • Metastatic renal cell carcinoma

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Surgery and Immediate Post-operative Care

Duration - Up to hospital discharge

Participants undergo nephron-sparing surgery for localized kidney tumors with perioperative data collection.

1 surgical procedure and hospital stay

Post-operative Follow-up

Duration - 60 months

Participants are followed up with questionnaires to assess kidney function, comorbidities, and survival over time.

Follow-up at 30 days, 12 months, 24 months, and 60 months

Trial Site Locations

Total: 5 locations

1

Sana Klinikum Hof

Hof, Bavaria, Germany, 95032

Actively Recruiting

2

MHH

Hanover, Lower Saxony, Germany, 30625

Actively Recruiting

3

Alexianer St. Hedwig-Krankenhaus

Berlin, Germany, 10115

Actively Recruiting

4

Vivantes Humboldt Klinikum

Berlin, Germany

Actively Recruiting

5

Saarland University

Homburg/Saar, Germany, 66421

Not Yet Recruiting

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Research Team

N

Nina Harke, Dr.

H

Heidrun Rexer

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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