Actively Recruiting
German National Registry for Nephron-Sparing Surgery for Localized Kidney Tumors
Led by Association of Urologic Oncology (AUO) · Updated on 2025-01-29
1000
Participants Needed
5
Research Sites
52 weeks
Total Duration
On this page
Sponsors
A
Association of Urologic Oncology (AUO)
Lead Sponsor
I
IAG-N at German Cancer Association (Deutsche Krebsgesellschaft e. V.)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are collecting data from patients undergoing partial nephrectomy, a kidney-sparing surgery, to treat localized kidney tumors. This observational registry study aims to identify key factors that influence the quality of surgical care by gathering detailed clinical and outcome information. The study focuses on understanding outcomes related to different surgical approaches, including open and minimally-invasive techniques like robotic surgery, which is increasingly used for complex tumors. Participants in this study undergo nephron-sparing surgery for localized renal masses, and their clinical data is recorded in the G-NeSS registry. The data collected includes patient details, tumor location and complexity, surgical approach, complications during and after surgery, and kidney function. Follow-up questionnaires are conducted at 30 days, 12 months, 24 months, and 60 months to monitor long-term kidney function, comorbidities, and survival. During the study, participants will have their clinical and surgical information recorded, with regular follow-ups to assess outcomes such as complication rates, kidney function measured by glomerular filtration rate, and survival over 60 months. This comprehensive monitoring helps researchers understand the long-term effects of partial nephrectomy and improve surgical care for patients with kidney tumors. Participation may last up to five years with these scheduled assessments.
CONDITIONS
Brief Title
German National Registry for NSS
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Written informed consent
- Localized kidney tumor suitable for nephron-sparing surgery
- Adequate abdominal imaging with contrast-enhanced CT or MRI
You will not qualify if you...
- Diagnosis or suspicion of urothelial cancer of the kidney
- Prior nephron-sparing surgery on the same kidney
- Metastatic renal cell carcinoma
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to hospital discharge
Participants undergo nephron-sparing surgery for localized kidney tumors with perioperative data collection.
1 surgical procedure and hospital stay
Duration - 60 months
Participants are followed up with questionnaires to assess kidney function, comorbidities, and survival over time.
Follow-up at 30 days, 12 months, 24 months, and 60 months
Trial Site Locations
Total: 5 locations
1
Sana Klinikum Hof
Hof, Bavaria, Germany, 95032
Actively Recruiting
2
MHH
Hanover, Lower Saxony, Germany, 30625
Actively Recruiting
3
Alexianer St. Hedwig-Krankenhaus
Berlin, Germany, 10115
Actively Recruiting
4
Vivantes Humboldt Klinikum
Berlin, Germany
Actively Recruiting
5
Saarland University
Homburg/Saar, Germany, 66421
Not Yet Recruiting
Research Team
N
Nina Harke, Dr.
H
Heidrun Rexer
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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