Actively Recruiting
Germline Genetic Testing of the TP53 Gene
Led by European Institute of Oncology · Updated on 2026-02-19
1940
Participants Needed
1
Research Sites
256 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a retrospective, observational, single-center study designed as a cohort analysis. The study population will include consecutive patients referred for genetic counseling and TP53 germline genetic testing between 2004 and 2025 at the Division of Cancer Prevention and Genetics of the IEO. The primary endpoint is to determine the overall detection rate of Pathological Variants (PVs) in the TP53 gene among individuals referred to the institute and the differences between the groups.
CONDITIONS
Official Title
Germline Genetic Testing of the TP53 Gene
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Have undergone at least one genetic counseling session at the Division of Cancer Prevention and Genetics of the IEO
- Have undergone germline TP53 genetic testing, regardless of referral criteria or testing approach
- Have provided written informed consent for participation in scientific research
You will not qualify if you...
- Have not signed informed consent for participation in scientific research
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Istituto Europeo di Oncologia
Milan, Italy, 20141
Actively Recruiting
Research Team
M
Mariarosaria Calvello, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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