Actively Recruiting

Phase Not Applicable
Age: 20Years +
All Genders
Healthy Volunteers
ID05800509

Gestational Diabetes and Depression in Pregnancy and the Postpartum Period Among Women: A Longitudinal Study and Interventive Program

Led by National Taiwan University Hospital · Updated on 2026-03-23

600

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

N

National Taiwan University Hospital

Lead Sponsor

M

Mackay Memorial Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research aims to explore the two-way relationship between gestational diabetes mellitus and perinatal depression, focusing on how prenatal depression may affect gestational diabetes and vice versa. The study also examines whether factors like social support, health behaviors, prenatal body index, weight gain during pregnancy, and perinatal complications influence this relationship. It addresses a gap in research, particularly in Asian countries, where such studies are limited. Participants diagnosed with gestational diabetes mellitus will be randomly assigned to one of two groups. One group receives access to a website offering health education with short video clips covering maternity management, healthy lifestyles, and partner support, while the other group receives access to a similar website without these clips. Both participants and their partners will complete structured questionnaires at 22 and 35 weeks of pregnancy, and at 3 and 6 months after delivery. Throughout the study, participants and their partners will provide information through questionnaires covering demographics, medical history, lifestyle, and knowledge about gestational diabetes. Participants will also record blood sugar levels and meal photos. Researchers will measure changes in depression, social support, physical activity, diet habits, body weight, BMI, health beliefs, and perinatal complications from the 22nd week of pregnancy to six months postpartum. The study includes ongoing monitoring and assessment of both maternal and infant health outcomes.

CONDITIONS

Brief Title

Gestational Diabetes and Perinatal Depression: an Intervention Program

Who Can Participate

Age: 20Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of gestational diabetes mellitus.
  • No history of diseases such as hypertension, diabetes mellitus, or hyperthyroidism before pregnancy, or if present, no medications taken.
  • No recurrent pregnancy loss and stable condition in the first trimester.
  • Use of a smartphone.
  • Willingness to participate in the study.
Not Eligible

You will not qualify if you...

  • Diagnosis of diabetes mellitus before pregnancy.

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Intervention and Questionnaires

Duration - From 22nd week to 35th week of pregnancy

Participants complete structured questionnaires at the 22nd week of pregnancy and receive a website of health education. The experimental group receives additional short educational clips on gestational diabetes and related health behaviors. Questionnaires and educational materials are also provided to their partners.

2 visits (in-person or remote) at 22nd and 35th weeks of pregnancy

Postpartum Follow-up and Questionnaires

Duration - From delivery to 6 months after delivery

Participants complete structured questionnaires and continue to access health education materials at 3 and 6 months after delivery to monitor depression, health behaviors, and perinatal outcomes.

2 visits (in-person or remote) at 3 and 6 months postpartum

Trial Site Locations

Total: 1 location

1

National Taiwan University Hospital

Taipei, Taiwan, 100

Actively Recruiting

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Research Team

H

HUNG-HUI CHEN

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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