Actively Recruiting
Get ActivE Study for At-risk Youth
Led by University of Pittsburgh · Updated on 2026-03-19
75
Participants Needed
2
Research Sites
92 weeks
Total Duration
On this page
Sponsors
U
University of Pittsburgh
Lead Sponsor
C
Children's Hospital of Philadelphia
Collaborating Sponsor
AI-Summary
What this Trial Is About
The study will adapt and deploy a digital Behavioral Activation app with mobile sensing, supported by health coaches, that encourages youth to engage in positive activities. The study has the potential to offer a low-cost and scalable behavioral intervention that may decrease risk of suicide among at-risk youth. This research will examine specifically whether an intervention involving an app called Vira, combined with health coaching (GET ActivE) can improve enjoyment for teens coping with depression. Research participants will be randomly assigned to one of two study intervention. One study intervention involves a) downloading an app called Vira and engaging by responding to a daily question, and b) participating in a conversation via text, phone, or messages through an appt with a health coach. The health coach will use the Vira app and principles from evidence-based therapy and behavior change to provide users with insights to sustain well-being and better manage risk factors for suicidal thoughts and behaviors such as depressed mood and behavioral withdrawal. The second study intervention involves downloading an app called EARS and responding to a daily question.
CONDITIONS
Official Title
Get ActivE Study for At-risk Youth
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adolescents age 12-18
- Current moderate to severe depression (PHQ-9-M > 11)
- Current clinically significant anhedonia, operationalized as PHQ-9-M anhedonia item score > 1
- English language fluency and literacy level sufficient to engage in study protocol
- Willing to download the app on their smart phones
You will not qualify if you...
- Evidence of mania, psychosis, or developmental disability that prevents understanding study procedures as determined by health records and phone screening
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
2
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, United States, 15213
Actively Recruiting
Research Team
B
Brandie George-Milford, MA
CONTACT
M
Morgan Rose, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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