Actively Recruiting

Phase Not Applicable
Age: 12Years - 18Years
All Genders
NCT06829953

Get ActivE Study for At-risk Youth

Led by University of Pittsburgh · Updated on 2026-03-19

75

Participants Needed

2

Research Sites

92 weeks

Total Duration

On this page

Sponsors

U

University of Pittsburgh

Lead Sponsor

C

Children's Hospital of Philadelphia

Collaborating Sponsor

AI-Summary

What this Trial Is About

The study will adapt and deploy a digital Behavioral Activation app with mobile sensing, supported by health coaches, that encourages youth to engage in positive activities. The study has the potential to offer a low-cost and scalable behavioral intervention that may decrease risk of suicide among at-risk youth. This research will examine specifically whether an intervention involving an app called Vira, combined with health coaching (GET ActivE) can improve enjoyment for teens coping with depression. Research participants will be randomly assigned to one of two study intervention. One study intervention involves a) downloading an app called Vira and engaging by responding to a daily question, and b) participating in a conversation via text, phone, or messages through an appt with a health coach. The health coach will use the Vira app and principles from evidence-based therapy and behavior change to provide users with insights to sustain well-being and better manage risk factors for suicidal thoughts and behaviors such as depressed mood and behavioral withdrawal. The second study intervention involves downloading an app called EARS and responding to a daily question.

CONDITIONS

Official Title

Get ActivE Study for At-risk Youth

Who Can Participate

Age: 12Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adolescents age 12-18
  • Current moderate to severe depression (PHQ-9-M > 11)
  • Current clinically significant anhedonia, operationalized as PHQ-9-M anhedonia item score > 1
  • English language fluency and literacy level sufficient to engage in study protocol
  • Willing to download the app on their smart phones
Not Eligible

You will not qualify if you...

  • Evidence of mania, psychosis, or developmental disability that prevents understanding study procedures as determined by health records and phone screening

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

2

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States, 15213

Actively Recruiting

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Research Team

B

Brandie George-Milford, MA

CONTACT

M

Morgan Rose, BS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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