Actively Recruiting

Phase Not Applicable
Age: 12Years - 18Years
All Genders
ID06829953

Geospatial and Ecological Momentary Assessment Technology and Activity Engagement for At-risk Youth Get ActivE Study for Adolescents with Depression and Suicide Risk

Led by University of Pittsburgh · Updated on 2026-06-04

75

Participants Needed

2

Research Sites

N/A

Total Duration

On this page

Sponsors

U

University of Pittsburgh

Lead Sponsor

C

Children's Hospital of Philadelphia

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating a digital behavioral activation program with mobile sensing and health coaching to support youth at risk of suicide, focusing on teens with depression and anhedonia. This trial aims to test whether the GET ActivE intervention, which combines the Vira app and personalized coaching, can improve enjoyment and well-being compared to activity monitoring alone. The study includes a randomized pilot trial with a diverse group of adolescents aged 12 to 18 years, exploring feasibility, acceptability, and equity of outcomes. Participants are randomly assigned to one of two groups. The first group uses the Vira app along with weekly support from a health coach who encourages engagement in positive activities through personalized nudges and messages based on mobile data and mood ratings. The second group downloads the EARS app to monitor activity and receives weekly summary reports via text messages. Both groups participate for up to three months, with follow-up assessments extending to 12 months. During the study, participants complete self-reports and mobile assessments related to mood, activity, and suicidal risk. Researchers monitor responses to health coach contacts, app engagement, and changes in anhedonia and depression severity over time. The study measures include feasibility, acceptability, appropriateness of the intervention, and equity of outcomes by race. Participants' activity patterns and mood are tracked digitally, and phone or message interactions with coaches are recorded to support behavior change and mental health management.

CONDITIONS

Brief Title

Get ActivE Study for At-risk Youth

Who Can Participate

Age: 12Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adolescents age 12 to 18 years
  • Current moderate to severe depression with PHQ-9-M score greater than 11
  • Clinically significant anhedonia with PHQ-9-M anhedonia item score greater than 1
  • English language fluency and literacy sufficient to participate
  • Willingness to download and use a smartphone app
Not Eligible

You will not qualify if you...

  • Evidence of mania, psychosis, or developmental disability that prevents understanding study procedures
  • Conditions identified through health records and phone screening that interfere with participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or remote) for eligibility assessment

Treatment

Duration - 3 months

Participants receive either the GET ActivE behavioral intervention involving a health coach and the Vira app to encourage activity and positive mood, or activity monitoring alone through the EARS app with weekly activity summaries.

Weekly contacts with a health coach for participants in the GET ActivE group; activity data collection via app for all participants

Follow-up

Duration - Up to 9 months after treatment (total follow-up up to 12 months from baseline)

Participants are assessed for intervention acceptability, appropriateness, and response to health coach contacts, with continued monitoring of anhedonia and mood outcomes.

Assessments at 1 month, 3 months, 6 months, and 12 months post-baseline

Trial Site Locations

Total: 2 locations

1

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

2

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States, 15213

Actively Recruiting

Loading map...

Research Team

B

Brandie George-Milford, MA

M

Morgan Rose, BS

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Similar Trials

Causal Role of Delta-beta Coupling for Goal-directed Behavio...

Major Depressive Disorder

Actively Recruiting

1 location

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here