Actively Recruiting
Glaucoma Rehabilitation Using ElectricAI Transcranial Stimulation (GREAT) - Randomized Controlled Trial Using Combined Perceptual Learning and Transcranial Electrical Stimulation for Vision Enhancement
Led by The Hong Kong Polytechnic University · Updated on 2024-10-29
144
Participants Needed
1
Research Sites
189 weeks
Total Duration
On this page
Sponsors
T
The Hong Kong Polytechnic University
Lead Sponsor
T
The University of Hong Kong
Collaborating Sponsor
AI-Summary
What this Trial Is About
Glaucoma is a complex disease that can result in progressive vision loss. It is the second leading cause of blindness, accounting for 23% of permanent blindness in Hong Kong. There are no treatments that restore vision lost to glaucoma. However, recent studies have shown that vision can be improved by perceptual learning (PL) and transcranial electrical stimulation (tES). This study will examine the effect of perceptual learning and tES on improving quality of life, visual function and functional performance in patients with peripheral field loss due to glaucoma. It is phase 2 of Glaucoma Rehabilitation Using ElectricAI Transcranial Stimulation (GREAT) project.
CONDITIONS
Official Title
Glaucoma Rehabilitation Using ElectricAI Transcranial Stimulation (GREAT) - Randomized Controlled Trial Using Combined Perceptual Learning and Transcranial Electrical Stimulation for Vision Enhancement
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age from 18 to 80 years
- Diagnosed with primary open angle or normal tension glaucoma affecting both eyes
- Relative scotoma with a Humphrey Field Analyser loss of mean deviation -6dB within central 24 degrees in at least one eye
- Best-corrected distance visual acuity of 6/12 or better
- Stable vision and visual field loss for at least 3 months
- Cognitive function score of 22 or above on Montreal Cognitive Assessment Hong Kong version
You will not qualify if you...
- Ocular diseases other than glaucoma such as age-related macular degeneration, diabetic retinopathy, or moderate to severe cataract
- Severe hearing impairment
- Severe medical issues like stroke or Parkinson's disease
- Neurological conditions including brain surgery, brain tumor, or peripheral neuropathy
- Cognitive disorders including diagnosed dementia or cognitive impairment
- Vestibular or cerebellar dysfunction or history of vertigo
- Use of medications for neurological or psychiatric conditions that affect motor control
- Contraindications for non-invasive brain stimulation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Hong Kong Polytechnic University
Hong Kong, Hong Kong
Actively Recruiting
Research Team
A
Allen Cheong, PhD
CONTACT
M
Melinna Mei, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
FACTORIAL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
3
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